Ch 3 oral pathology (in red) part 2
About this set
Created by:
Jackiedh on September 11, 2011
Subjects:
Description:
oral path the immune response
Classes:
NTCC Dental Hygiene 13, SLCC DH
Log in to favorite or report as inappropriate.
Order by
114 terms
Terms | Definitions |
|---|---|
 what is the FIRST line of defense against tissue injury and disease producing microorganisms? | ACUTE INFLAMMATION |
| IMMUNE response occurs AFTER the __________ response. needed for COMPLETE _________ | inlammatory recovery |
| what is the difference btw inflammatory response and immune response? | immune response can REMEMBER and RESPOND MORE QUICKLY to a foreign substance encountered 2 or more times! |
| which WBC's are the MAIN part of IMMUNE response? | LYMPHOCYTES |
| MOST antigens are _________ | proteins! |
| what do antigens include? (3) | microorganisms (+by products) transformed human cells (tumors/viruses) human tissue (organ trans, graft or incomp. blood) |
| with AUTOIMMUNE DISEASE, a persons own body sees part of itself as an __________ | ANTIGEN |
| name the 4 cells involved in the immune response | 1. B lymphocytes 2. T lymphocytes 3. Natural killer (NK) 4. Macrophage |
| which lymphocytes are acquired immunity? | T lymphocytes |
| which lymphocytes make plasma cells and are acquired? | B lymphocytes |
| which cells are innate immunity (automatic) and act against viruses and cancer cells? | NK cells |
| macrophages are ________ (natural) | innate |
| natural killer cells are __________ (WBC's) | lymphocytes |
| which cells are lymphocytes, have innate immunity (not involved with acquired), in the microcirculation, and active against viruses and cancer cells? | NK Cells |
| what is the abnormal function of NK cells? | when they are against several immunodeficiency syndromes |
| which WBC's are able to RECOGNIZE and RESPOND to an antigen? | lymphocytes |
| lymphocytes are derived from a _______ _______ in the bone marrow | STEM CELL |
| lymphocytes make up ___-___% of the entire WBC population | 20-25% |
| lymphocytes are antigen-________, ________ lived, and ________ | antigen sensitive long-lived mobile |
| t/f different types of lymphocytes all do the same thing | FALSE! different ones do different things (imagine that!) |
| t/f B lymphocytes go through the thymus | FALSE! THEY DO NOT!!!! |
| what are the two main types of lymphocytes? | B cells T cells |
| where does an NK cell come from? | the bone marrow |
| NK cells are part of the bodies ______ immunity, they _______ cells that are recognized as foreign | inborn destroy |
| nk cells function in the ______ phases of the immune response (unknown) | EARLY |
| t/f macrophages are involved in the immune response | true |
| what do plasma cells produce? | antibodies |
| what cell gives response to the antigen? | plasma cells |
| what is another term for antibodies? | immunoglobulins (hence: Ig's) |
| where are Igs carried? | in the bloodstream |
| name the 5 different ANTIBODIES (hint Ig's) | A,D,E,G,M IgA IgD IgE IgG IgM |
| which two antibodies activate the B lymphocytes? | IgM and IgD |
| ____ = major Ab in blood serum (1st passive immunity of a newborn) | IgG |
| ____= hypersensitivity; binds to mast cell (histamine) this one will cause anaphylaxis, asthma | IgE |
| ____= serous (blood) and secretory (saliva) defends against proliferation of microorganisms in the BODY | IgA |
| the level specific antibody in the blood is what? | antibody titer |
| immune complex = when an ______ combines with a __________ | ANTIBODY ANTIGEN |
| T lymphocytes travel to the ______ (major organ of lymphoid development) to mature | THYMUS |
| what are the two different T lymphocytes with different jobs? | memory cells t-helper cells (helps B-cells) |
| t-helper cells _______ the function of b-cells t-helper cells ________ the antibody response | increase enhance "T" is for terrific! |
| which cells suppress the function of b lymphocytes? | t-suppressor cells |
| which cells are active in surveillance against virally infected or tumor cells? | t-cytotoxic cells |
| t/f macrophages are in microcirculation | FALSE!!!!!!! no they ain't |
| what live in the CT during inflammation? | macrophages |
| what help out the b and t cells? | macrophages |
| what do macrophages do for lymphocytes? | process the antigen cell |
| once the lymphocytes are stimulated, where do they go? | leave lymphoid tissue and travel to the site of injury |
| ____________ SERVE AS THE LINK BETWEEN THE INFLAMMATORY AND IMMUNE RESPONSE | MACROphages |
| macrophages are the link between what? | inflammatory and immune response |
| t/f macrophages have the capacity to remember | sorry, afraid not |
| t/f macrophages need reactivation during each encounter of foreign objects | true! they gots the alzheimers |
| which lymphocytes make plasma cells and the plasma cells make antibodies? | b lymphocytes |
| which cells HELP enhance the antibody and the SUPPRESSORS turn off the b cells? | t lymphocytes (t-helpers, t-suppressors) |
| which cells link inflammation and immunity and amplify the immune response? | macrophages |
| which cells are in microcirculation, innate immunity, and attack viruses and cancer cells? | NK cells |
| what are the four bone marrow white blood cells? | neutrophil monocytes b-cells t-cells |
| monocytes are _______ nucleated and macrophages are _________ nucleated neutrophils are _________ nucleated | single multiple multiple |
| where do the neutrophils, monocytes, b cells, and t cells come from? | bone marrow-stem cell |
| immunoglobulins are made from _______ cells | plasma |
| which cells make the antibodies? which cells make the plasma cells? | plasma cells b cells |
| which cells make the blast, memory, helper, suppressor, and killer? | t-cells |
| ________ are proteins made by cells of the immune system | cytokines |
| cytokines play a role in _________ btw lymphocytes and other immune system | communication |
| __________ are cytokines produced by b an t cells | lymphokines |
| ________ are cytokines produced by macrophages | monokines |
| __________ is produced by t cells and macrophages (antiviral) | interferon*** |
| __________ induce directed chemotaxis in responsive cells | chemokines |
| cytokines ______ macrophages to enhance ability to destroy foreign cells | activate |
| what are the two MAJOR divisions of the immune response? | humoral response cell-mediated response |
| which response is antibody production? | HUMORAL |
| what are the PRIMARY cells in the humoral response? | B cells (remember? B Funny) |
| what response protects against bacteria/viruses? | humoral |
| which response has lymphocytes working alone? | cell-mediated response |
| which are the PRIMARY cells in the cell mediated response | T Cells |
| which response regulates the other response? | Cell-mediated regulates the humoral response |
| ________= increased responsiveness as a result of memory | immunity |
| name the two types of immunity | active passive |
| what is the acquired ACTIVE immunity? | vaccine-injected microorganism |
| what is the Natural ACTIVE immunity? | microorganism |
| what is the Acquired PASSIVE immunity? | antibodies injected (interferon) |
| what is the Natural PASSIVE immunity? | mother to fetus (from placenta) |
| vaccine = ________ antibodies =__________ | antigen memory |
| what is the study of the immune reactions involved in disease? | immunopathology |
| what does the immune response help defend the body against? what does malfunction do? | attacks attacks the individual |
| IMMEDIATE allergic rxn = type ____ hypersensitivity | I |
| IgE (__________) mediated mast cells release _________ | HUMORAL histamine |
| EDEMA increases _______ and permeability of the BV. it also __________ smooth muscles in bronchiols | dilation constriction |
| anaphylaxis is a type ___ rxn | I (ie: asthma) |
| type I hypersensitivity = allergen ---> _______ cell ---->IgE (antibody) ----> histamine ----> _______ ---->anaphylaxis | plasma cell edema |
| type II hypersensitivity is ______ | cytotoxic |
| when an antibody combines with an antigen bound to the surface of the tissue cell (RBC), it is type ___ | II hypersensitivity |
| IgG and IgM (humoral)= type ____ | II |
| type I, II, and III are all ________ responses | HUMORAL! |
| type III hypersensitivity is formed btw microorganisms and _________ in the circulating blood | antibodies |
| deposition of the complexes leaving the blood in type III hypersensitivity result in initiation of ________ _________ _______ | acute inflammatory response |
| ________ are attracted to tissues in type III hypersensitivity | neutrophils |
| __________ and _________ death release lysosomal enzymes in type III hypersensitivity | phagocytosis and neutrophil death |
| type III hypersensitivity has tissue ______ | destruction |
| which type of hypersensitivity can lead to autoimmune diseases such as lupus erythematosus? | III |
| type ____ is cell-mediated, delayed | IV |
| which type of hypersensitivity is cell-mediated, not humoral? | type IV |
| _____ cells KNOW the antigen causes damage to tissue cells themselves | T |
| which route of administration is worse, it can go systemic? | INJECTION |
| t/f pt's with an infection are more likely to have an allergic response | ture |
| pt's with multiple allergies/autoimmune disease have a high _______ with epi | allergenicity (more in adults) |
| __________ are less likely to have problems than _________ with type IV hypersensitivity | children adults |
| contact dermatitis or mucositis is an example of type _____ hypersensitivity | IV |
| t/f all four types of hypersensitivity are involved in drug hypersensitivity | true |
| what type of hypersensitivity to drugs is hemolytic anemia? | type II |
| what type of hypersensitivity to drugs is serum sickness? | type III |
| what type of hypersensitivity to drugs is anaphylaxis, urticaria, angioedema? | type I |
| when the immune system learns difference between self and foreign (during embryologic development) | immunologic tolerance |
| autoimmune disease is also known as what? | connective tissue diseases |
| congenital is at _______ and acquired is development after ______ | birth birth |
First Time Here?
Welcome to Quizlet, a fun, free place to study. Try these flashcards, find others to study, or make your own.