Marieb Human A&P: Ch 3: Cells, The Living Units (Parts B-D)

About this set

Created by:

teensleuth  on September 17, 2011

Subjects:

anatomy, physiology, biology

Description:

Cytoplasm, Nucleus, Cell Growth and Reproduction, Extracellular Material; Instructor: Dr. Evan Greller

Classes:

Cell division

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Marieb Human A&P: Ch 3: Cells, The Living Units (Parts B-D)

Cytosol
Water with solutes in it (protein, salts, sugars, etc)
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Terms

Definitions

Cytosol Water with solutes in it (protein, salts, sugars, etc)
Cytoplasmic organelles The different types make up the metabolic machinery of the cell
Cytoplasm The intracellular fluid and its contents; located between plasma membrane and nucleus
Membranous organelles Mitochondria, peroxisomes, lysosomes, endoplasmic reticulum, Golgi apparatus (what do these have in common?)
Nonmembranous organelles Cytoskeleton, centrioles, ribosomes
Mitochondria The "generator" of the "cell as a factory" model. Produces ATP
Mitochondria Contains its own DNA and RNA, in addition to that of the nucleus
Mitochondria This organelle produces ATP
Ribosomes These organelles are the sites of protein synthesis
Free-floating ribosomes These types of ribosomes synthesize soluble proteins
Membrane-bound (on rough ER) ribosomes These ribosomes synthesize proteins to be incorporated into membranes or exported from the cell
Endoplasmic reticulum This organelle extends continuous from the nuclear membrane
Endoplasmic reticulum Made of two varieties: rough ER and smooth ER
Rough ER Manufactures all secreted proteins, as well as membrane-integral proteins and phospholipids
Smooth ER Synthesizes steroid-based hormones
Smooth ER in intestinal cells Absorption, synthesis, transport of fats
Smooth ER in skeletal and cardiac muscle Storage and release of calcium
Golgi apparatus In the "cell as a factory" model, this is the packaging department
Golgi apparatus Modifies, concentrates, and packages proteins and lipids
Lysosomes In the "cell as a factory" model, these are waste containers
Lysosomes These spherical, membranous bags contain DIGESTIVE ENZYMES which can break down nonfunctional organelles, glycogen, and bone to release Ca2+
Endomembrane system The overall function of this intercellular system is to produce, store and export biological molecules
Endomembrane system flow chart Nuclear membrane > endoplasmic reticulum > Golgi apparatus > lysosomes
Peroxisomes These organelles contain powerful enzymes that detoxify harmful or toxic substances
Cytoskeleton This organelle is composed of an elaborate series of rods through the cytosol
Cytoskeleton's three component parts Microtubules, microfilaments, intermediate filaments
Microfilament of the cytoskeleton This component of the cytoskeleton is involved in cell motility, change in shape, endocytosis and exocytosis
Intermediate filaments of the cytoskeleton This component of the cytoskeleton can resist pulling forces on the cell and attach to desmosomes
Microtubules of the cytoskeleton This component of the cytoskeleton which radiates from the centrosome determines the overall shape of the cell and distribution of organelles
Centrosome Center area of cell, region around the nucleus, cell center
Centrosome Generates microtubules and organizes the mitotic spindle
Mitotic spindle Pertains to the splitting of a cell during reproduction
Centrosome This area of the cell contains centrioles, small tube formed by microtubules
Three types of membrane junction Tight junction, Desmosome, Gap junction
Tight junctions of cells These membrane junctions prevent fluids and most molecules from moving between cells; found in stomach, mouth, epithelial tissue
Desmosomes (membrane junction) These membrane junctions "rivet" or "spot weld" to anchor cells together; found in skin and areas of high friction
Gap junctions of cells These membrane junctions are formed by transmembrane pores that allow small molecules to pass from cell to cell; found in cardiac and smooth muscle cells
Cilia This cell extension moves substances across cell surfaces
Flagella This cell extension is found in only one cell type in the body, sperm cells; propel whole cells
Microvilli This cell extension are finger-like extensions of the plasma membrane that increase surface area for more absorption
Nucleus In the "cell as a factory" model, this is the central management office
Nucleus This organelle houses the genetic library with blueprints for nearly all cellular proteins
DNA Genetic blueprint material that is housed in the nucleus of all cells
Nuclear envelope A double-membrane layer that houses the nucleus; its outer layer is continuous with the rough endoplasmic reticulum and bears ribosomes
Nucleoli These structures within the nucleus are involved in rRNA synthesis and ribosome subunit assembly
Chromatin This material is made up of 30% threadlike strands of DNA, 60% histone proteins, and 10% RNA
Chromatin This material condenses into bar-like bodies called chromosomes when the cell starts to divide
Chromatin Its structure can be likened to "beads on a string," with the "beads" being histones and the "string" being strands of DNA
Interphase This phase of the cell cycle defines most of its life; from cell formation to cell division
Mitotic phase This phase of the cell cycle is when reproduction happens
Four subphases of interphase G1 (gap 1), G0 (gap 0), S (synthetic), G2 (gap 2)
G1 subphase This subphase of interphase is marked by vigorous growth and metablolism
G0 subphase This subphase of interphase is a gap phase where cells permanently cease dividing
S (synthetic) subphase This subphase of interphase is marked by DNA replication
G2 subphase This subphase of interphase is marked by preparation for cell division
Nucleotide One half of a strand of DNA or RNA
Nucleotide In DNA replication, each strand of this serves as a template for building a complementary new strand
Helicase This enzyme begins the "unzipping" of a DNA helix for replication
DNA replication End result of this process is that two DNA molecules are formed from the original
Mitotic phase This phase of the cell cycle is when reproduction and division happens
Four subphases of nuclear division Prophase, metaphase, anaphase, telophase
Cytokinesis The division of cytoplasm by a cleavage furrow; literally translates to "cell splitting"
Early prophase In this subphase of cell division, chromosomes become visible, centrosomes separate and migrate toward opposite poles and mitotic spindles and asters form
Centromere The center portion of the "X" of a chromosome
Mitotic spindle The centrosomes act as focal points for growth of these microtubule assemblies; as these lengthen, they propel the centrosomes toward opposite ends of the cell
Late prophase In this subphase of cell division, the nuclear envelope fragments, kinetochore microtubules attach to kinetochore of centromeres and draw them toward the equator of the cell, and polar microtubules assist in forcing the poles apart
Metaphase In this subphase of cell division, the two centrosomes are at opposite poles of the cell, while the chromosomes cluster at the middle with their centromeres precisely aligned with the equator of the spindle
Metaphase plate The imaginary plane midway between the cellular poles during the cell division subphase of metaphase
Anaphase In this, the shortest subphase of cell division, The centromeres of the chromosomes split simultaneously and the chromatids become chromosomes. The moving chromosomes look "V" shaped
Telophase In this subphase of cell division, chromosomal movement stops and chromosomes uncoil; new nuclear envelopes form and mitosis ends
Cytokinesis In this action which completes cell division, a ring of actin microfilaments contract to form a cleavage furrow that splits the cell's cytoplasm
"Go" signals of cell division Critical volume of cell when area of membrane is inadequate for exchange; Chemicals (hormones, enzymes) can also serve this function
"Stop" signals of cell division Contact inhibition (wear and tear on cells); growth-inhibiting factors produced by repressor genes
Gene Segment of DNA with blueprint for one polypeptide
Polypeptide A chain of amino acids (another name for a protein)
Triplets of nucleotide bases Ex: AGC, TAA These each encode one specific amino acid
Messenger RNA (mRNA) Carries instructions for building a polypeptide, from GENE IN DNA TO RIBOSOMES IN CYTOPLASM
Ribosomal RNA (rRNA) Structural component of ribosomes that, along with tRNA, helps translate messages from mRNA (This is the "docking station")
Transfer RNA (tRNA) BIND TO AMINO ACIDS and pair with bases of codons of mRNA at ribosomes to begin process of protein synthesis
RNA transcription Transfers DNA gene base sequence to a complementary base sequence of an mRNA
RNA polymerase Enzyme that oversees the synthesis of mRNA

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