A normal process accompanied by a progressive alteration of the body's homeostatic adaptive responses; produces observable changes in structure and increases vulnerability to environmental stress and disease.
The branch of medicine devoted to the medical problems and care of elderly persons.
Specific DNA sequences found only at the tips of each chromosome.
Produce oxidative damage in lipids, proteins, or nucleic acids by "stealing" an electron to accompany their unpaired electrons; cause wrinkled skin, stiff joints, and hardened arteries.
A disease characterized by normal development in the first year of life followed by rapid aging; caused by a genetic defect in which telomeres are considerably shorter than normal.
A rare, inherited disease that causes a rapid acceleration of aging, usually while the person is only in his or her twenties; characterized by wrinkling of the skin, graying of the hair and baldness, cataracts, muscular atrophy, and a tendency to develop diabetes mellitus, cancer, and cardiovascular disease.
A group of diseases characterized by uncontrolled or abnormal cell division.
When cells in a part of the body divide without control, the excess tissue that develops is called a _______.
The study of tumors.
A cancerous neoplasm is called a...
The spread of cancerous cells to other parts of the body.
A neoplasm that does not metastasize (like a wart).
Malignant tumors that arise from epithelial cells.
Cancerous growths of melanocytes (skin epithelial cells that produce the pigment melanin).
A general term for any cancer arising from muscle cells or connective tissues.
The most frequent type of childhood cancer that destroys normal bone tissue.
A cancer of blood-forming organs characterized by rapid growth of abnormal leukocytes (white blood cells).
A malignant disease of lymphatic tissue -- for example, of lymph nodes.
The growth of new networks of blood vessels.
tumor angiogenesis factors (TAFs)
Proteins that stimulate angiogenesis in tumors.
A chemical agent or radiation that produces a cancer.
Permanent changes in the DNA base sequence of a gene.
Normal genes are called...
Viruses that cause cancer by stimulating abnormal proliferation of cells.
A multistep process of cancer development in which as many as 10 distinct mutations may have to accumulate in a cell before it becomes more cancerous.