| Term | Definition |
|---|
| Fraction of world's population infected with TB | 1/3 |
| Deaths worldwide from TB | 1.5 - 3 million |
| Percentage of US adults who test positive for TB | 15 |
| Scrofula | swollen lymph glands of the neck |
| Pott's Disease | Deformity of the spine, leads to hunchback |
| Lupus Vulgaris | TB of the skin, infection via a cut |
| Pulmonary | TB of the lungs, most common, AKA consumption |
| Mycobacterium tuberculosis | Cause of TB, grows in lungs |
| Phagocytes have trouble | because an unusual waxy cell wall prevents digestion by the phagocyte |
| symptoms of TB | fever, fatigue, weight loss, cough with bloody sputem |
| Transmission | through breathing |
| Reinfection | Different strains of TB (about 50) and our immune memory isn't great, sometimes the immune response weakens |
| Reason for increase in 17th century | Shift to urban living, lots of town dairies, bad sanitation and close quarters |
| Sanatoria | isolation in areas with fresh air, health effects are questionable |
| Chemotherapy | Prevents mycolic acid cell wall synthesis, but takes a long time (up to 6 months) |
| Tuberculin skin test | Used in US to screen for TB, for populations that haven't been vaccinated, it tells if you have infection or not |
| Tuberculin Reaction | Hardening/reddening of skin in 48 hours is a positive test |
| BCG Vaccine | Attenuated, works in varying degrees, good in developing countries |
| Attenuated | Taking bacteria that causes diseases and growing it in the lab for many generations. This weakens it. |
| US and BCG Vaccine | Attenuated live vaccine could mutate and become virulent, makes TB test useless |
| XDR-TB | Extensively drug resistant TB resists 3 or more of the 6 classes of second-line drugs |
| AIDS and TB | AIDS speeds process from latent to active TB |
Combine with other sets
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