Chp 10 -Nervous System

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krae6972  on September 25, 2011

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Chp 10 -Nervous System

CNS includes
brain, spinal cord, nerves
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Definitions

CNS includes brain, spinal cord, nerves
PNS includes peripheral nerves
peripheral nerves do what connect CNS to other body parts
sensory neurons travel from 1 of our senses (organs) to brain- afferent
motor neurons take a return message from brain to sense (organ) -efferent
2 types of motor neurons somatic-voluntary
autonomic-involuntary
detect changes sensory receptors aka affectors
collect sensory info, make decisions integritive functions
responds to muscles, glands motor impluses aka effectors
affectors receive signal
effectors carries away
nerve cell neuron
basic unit neuron
function of neuron transmits nerve impulses along nerve fibers to other neurons or cells outside CNS
nerve bundle of axons
nerve impulses aka electrochemical changes
neuroglia does not transmit nerve impulses, fill spaces, supports and nourishes neurons
space between neurons synapse
bipolar 1 axon, 1 dendrite
bipolar found in eyes nose ears
unipolar 2 branches and function as axon
ex of unipolar ganglia- large nerve tissue
multipolar many dendrites
ex of multipolar most common in brain and spinal cord
most unipolar, some bipolar sensory
multipolar interneuron (association)
efferent motor
4 neuroglia functions stim neurons in embryo, nourish neurons, remove ions and neurotransmitters, provide support
cool fact about neuroglia smler than neurons but out number than 5-10x
more than 1/2 brain volume neuroglia
most brain tumors because neuroglia cells divide too often
neurons and neuroglia develope the same ___ neural stem cells
microglia (in brain) causes huntingtons disease, releases toxins that damage neurons
astrocyte causes lou gherigs disease- releases toxins than destroy certain motor neurons
2 types of neuroglia in the PNS schwann cells, satellite cells
schwann cells produce myelin ( on nerve in PNS)
satellite support the ganglia- masses of nerve cells
4 types of neuroglia found in the CNS astrocytes, oligodendrocytes, microglia, ependyma
astrocytes star shaped, connect neurons to blood vessels
oligodendrocytes form myelin sheath in brain and spinal cords
microglia sml, provide support and perform phagocytosis
ependyma inner lining of brain and spinal cord, allow for diffusion between fluid in brain and spinal cord
injured cell body, the nerve will most likely die
damaged peripheral nerve distal part dies, neuroglia secrete nerve growth factors, proximal may reestablish connections by conn tiss tube, growth is 3-4 mm day
CNS regeneration is very unlikely
3 characteristics to myelination begins 14th week of gestation, incomplete at birth, continues through adolescence
functional connection between 2 neurons synapse
gap between area of synapse synaptic cleft
presynaptic neuron before it goes across gap
postsynaptic neuron after it goes across gap
synaptic transmission process impulse travels from presynaptic neuron to postsynaptic neuron
process 6 steps nerve impulse, synaptic knob, synaptic vessicles, neurotransmitter, synaptic cleft, receptor molecules
synaptic vessicles hold what neurotransmitters
neurotransmitter goes across gap ( synaptic cleft)
receptor molecules aka port
neurotransmitter thats exitatory getting stimulated
neurotransmitter thats inhibitory body wants to shut off process
whatever the body wants to happen will determine if its inhibitory or excitatory
polarized electrical charge at membrane
if the outside of the cell membrane is + the inside will be -
inside - outside + happens when no nerve impulse is going through
what are the 2 ions of the cell membrane Na+, K+
3 Na out for ever 2 K+ in, ends up with net + on outside
resting potential no stimulation, when no impulse is going through, inside - outside + (net of 1 K+ outside)
local potential changes when the nerve impulse message is now going through the axon, change in pot voltage, opens ion channel for Na allowed in a K let out, changes the charge
cell membrane potential aka voltage
action potential change in charge itself
depolarization of cell membrane + inside, - outside
once the nerve impulse leaves the cell repolarization happens, - inside, + outside,
nerve impulse series of 1 action after another, polarization to depolarization over and over
all or none response is like muscle fiber responses
all or none response includes all contracts or all doesnt, nerve impulse conduction completely or not at all (neuron)
nerve impulse goes faster in what? myelinated than unmyelinated
the larger the diameter, the __ faster the nerve impulse goes through
unmyelinated travels full length surface of axon
nodes of ranvier has breaks, nodes in axon (with schwann cell)
impulse conduction saltatory conduction
2 types of synaptic potentials( charge/voltage at synapse) EPSP, IPSP
EPSP excitatory post synaptic potential
IPSP inhibitory post synaptic potential
EPSP increases what Na+
IPSP increases what K+
there are how many types of neurotransmitters 30+
acetyl choline (ACH) stim skeletal muscle contraction
Monoamines epinephrine (adreniline), norepenephrine, dopamine, seratonin
amino acids glycine, glutamic acid, gamma-- amino butyric acid (GABA)
peptides short chains of amino acids
peptide neurotransmitters (neuropeptides) enkephalins, endorphins- stronger (pain relivers) substance P- sends pain impulses to spinal cord
nitric oxide gasses, may play role in memory
neuronal pools process CNS neurons into pools
afferent impulse- pool--processing--efferent
pool neurons clustered together
convergence coming into spinal cord and brain
divergence going away from spinal cord and brain, some get left in pool, other go out with other motor neurons
divergence means 1 neuron goes to several parts of the body
dilantin sedative, promotes Na+, K+ pump, gets action nerve potential working right
caffeine stimulant, lowers threshold of stimulus so body rx a lot quicker
cocaine prevents inactivation of norepinephrine
valium causes relaxtion, inhibits seizures/anxiety, increases effect of GABA
anphetamines promotes dopamine release, makes people feel good but just for a moment, strong high happy
lsd hallucination, stimulates and binds with seratonin

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