#15 Additive and Synergistic Effects of Antibiotics

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goal of antibiotic combination therapy

a) reduce the incidence of antibiotic resistance b) allow lower does of antibiotics to be used c) enhance agents antibacterial activity

additive effect

overall effect of the antibiotic combination is no greater than the sum of individual antibiotics(own zone)

synergistic effect

overall effect of antibiotic combination is greater than the sum of the individual antibiotics.(zones merge)

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