| Term | Definition |
|---|
| keratinocytes, melanocytes, Langherans cells, Merkel cells | four principal cells found in epidermis |
| keratinocytes | 90% of epidermal cells |
| keratinocytes | arranged in 4-5 layers and produce a protective water-resistant protein |
| melanocytes | 8% of epidermal cells |
| melanocytes | transfer melanin granules that cluster to guard nucleus to keratinocytes |
| melanin | brown-black pigment that absorbs UV light and contributes to skin pigment |
| Langherans cells | migrate to epidermis from RB marrow, contribute to immune responses |
| Merkel cells | in stratum basale, detect touch sensations |
| basale, spinosum, granulosum, lucidum, corneum, CLGSB | the five strata of epidermis from deep to superficial, AND acronym |
| basale | single row of cuboidal or columnar keratinocytes, some are stem cells, desmosomes and hemidesmosomes bind. All principal cells found, exc. melanocytes |
| spinosum | 8-10 layers, flatter than basal. L and M cells found, some mitosis still occurs |
| granulosum | 3-5 layers, apoptosis begins, keratin develops from tonofilaments |
| lucidum | only in thick skin, 5 layers of clear dead keratinocytes |
| corneum | 25-30 layers, shedding |
Combine with other sets
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