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Where is the primary location of biotransformationor metabolism of aminde type anesthetic? Liver Where is the primary location of biotransformation or metabolism of ester-type anesthetic? Plasma Patients with atypical pseudocholinesterase should not recieve ester type local anesthetics because they lack the enzyme necessary to metabolize the local anesthetic agent. True All injectable local anesthetic drugs used in dentistry are: Vasodilators Local anesthetics have the greatest effect on which of the following tissues: CNS The half-life of a local anesthetic is which of the following? The rate at which the local anesthetic is eliminated from the blood. local anesthetics cross the blood-brain barrier. However they do not cross the placenta or enter the blood stream of the developing fetus. the first statement is true and the second statement is false The maximum number of carpules if anesthetic for a ( normal healthy) patient is usually restricted by what factor contained in the local anesthetic solution? local anesthetic drugs The maxium safe dose of the vasoconstrictor epinephrine, at one setting, is approximately 0.2 mg for the (normal healthy) adult patient. In a 1:100,000 solution, this would translate into how many carpules: 11 carpules Upon injection of an anesthetic containing a vasoconstrictor, all the following solutions occur exept one? Decreased duration of anesthesia A 1:100,000 concentration of epinephrine in a local anesthetic solution is the most common concentration used. A 1:200,000concentration contains twice as much vasoconstrictor than the 1:1,00,000 concentration The first statement is true and the second statement is false Which of the following is not a routine function of a vasoconstrictor? it doesnt increased the heart rate to prevent hypotension Which is the following is the strongest/most potent vasoconstrictor? 1:100,000 epinephrine Which of the following os an absolute contraindication to the use of Levonordefrin? Patient taking oral tricyclic antidepressants(TCA's) Which of the following is a CNS reaction to an overdose of a local anesthetic solution? Convulsions