Big gun, DOC for MRSA
What is Vancomycin used for
Aminoglycosides, Vancomycin, and Quinolones. All others are just bacteriostatic
What are the bactericidal Antibiotics
Aerobic gram negative only
What types of bacteria do aminoglycosides kill
Aminoglycosides + _________ = ototoxic
Contraindicated for those under 16 b/c of their effects on joint cartilage. They should be used with caution in those over 60 b/c increased risk to tendinopathy.
For quinolones, what group are they contraindicated in and what group should they be used with caution
Quinolones, azoles, NNRTIs and protease inhibitors, nicardipine, TCAs, many arrhthmics, many antipsychotics, some SSRIs. Never combine two of these drugs!
What drugs increase QT intervals
Sulfonamides inhibit folate synthesis, Trimethoprim inhibits folate use. Used alone they are bacteriostatic, used together they are bactericidal
Which class of drugs inhibit folate synthesis? Folate use?
What antibiotic is a cell wall synthesis inhibitor, but can only be used topicallly b/c it is very nephrotoxic
Most of the gram positive and many gram negative (most of the enterobacteriaceae). They work on both aerobic and anaerobic and are super resistant to b-lactamases. Great wide spectrum AB
What kind of bacteria do carbapenems target
What ending is associated with carbapenems
What ending is generally associated with aminoglycosides
Vancomycin and Teicoplanin
Name the two most common glycopeptide antibiotics
Only effective against gram positive bacteria and usually only used as a last resort in serious infections. Their side effect: Red Man Syndrome (erythema and hypotension caused by their release in histamines)
What are vancmycin and Teicoplanin used to treat and what is their famous side effect
What antibiotic is effective agains anaerobic bacteria and many protozoa
What antibiotic accumulates well in urine making a great drug to treat UTIs? (Its also the DOC of UTIs in pregnant women)