Chapter 5 - The Integumentary System Part 1

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The apocrine sweat glands are fairly unimportant in thermoregulation.

TRUE

Skin surface markings that reflect points of tight dermal attachment to underlying tissues are called epidermal ridges.

FALSE

The dense fibrous connective tissue portion of the skin is located in the reticular region of the dermis.

TRUE

The outermost sheath of a hair follicle is the connective tissue root sheath.

TRUE

The protein found in large amounts in the outermost layer of epidermal cells is collagen.

FALSE

Joe just burned himself on a hot pot. A blister forms and the burn is painful. Joe's burn would best be described as a third-degree burn.

FALSE

Destruction of the matrix of the hair bulb would result in its inability to produce oil.

FALSE

The hyponychium is commonly called the cuticle.

FALSE

The reason that the nail bed appears pink is the presence of a large number of melanocytes in the underlying dermis.

FALSE

During the resting phase of hair growth, the matrix is inactive and the follicle atrophies.

TRUE

The most dangerous skin cancer is cancer of the melanocytes.

TRUE

The skin is not able to receive stimuli because the cells of the epidermis are not living and therefore there are no sensory receptors in the skin.

FALSE

The dermis is rich in blood vessels and nerve fibers.

TRUE

The hypodermis is composed of adipose and dense connective tissue.

FALSE

A physician is often able to detect homeostatic imbalances in the body by observing changes in the skin color.

TRUE

When an individual is exposed to extremely low air temperatures, the dermal blood vessels will dilate so that blood and heat will be dissipated.

FALSE

Regardless of race, all human beings have about the same number of melanocytes.

TRUE

Ceruminous glands are modified merocrine glands.

FALSE

The stratum corneum (outermost layer of skin) is a zone of approximately four layers of viable cells that are able to synthesize proteins that keep the outer layer of skin smooth and soft.

FALSE

The dermis has a connective tissue and adipose layer that loosely binds the body together.

FALSE

Incisions should be made across rather than parallel to cleavage lines produced by collagen fiber bundles.

FALSE

The pinkish hue of individuals with fair skin is the result of the crimson color of oxygenated hemoglobin (contained in red blood cells) circulating in the dermal capillaries and reflecting through the epidermis.

TRUE

Hair growth and density are influenced by hormones, nutrition, and, in some cases, lifestyle.

TRUE

When a patient is said to have "third-degree burns," this indicates that the patient has burns that cover approximately one-third of the body.

FALSE

Sweat glands continuously produce small amounts of sweat, even in cooler temperatures.

TRUE

Select the most correct statement concerning skin cancer.
A) Most tumors that arise on the skin are malignant.
B) Squamous cell carcinomas arise from the stratum corneum.
C) Basal cell carcinomas are the least common but most malignant.
D) Melanomas are rare but must be removed quickly to prevent them from metastasizing.

D) Melanomas are rare but must be removed quickly to prevent them from metastasizing.

________ is an inherited condition that affects the heme pathway; it leaves the skin scarred and gums degenerated, and may have led to the folklore about vampires.
A) Porphyria
B) Decubitus ulcer
C) Impetigo
D) Rosacea

A) Porphyria

A needle would pierce the epidermal layers of the forearm in which order?
A) basale, spinosum, granulosum, corneum
B) basale, spinosum, granulosum, lucidum, corneum
C) granulosum, basale, spinosum, corneum
D) corneum, granulosum, spinosum, basale

D) corneum, granulosum, spinosum, basale

The major regions of a hair shaft include all of the following except ________.
A) medulla
B) cortex
C) external root sheath
D) cuticle

C) external root sheath

Acne is a disorder associated with ________.
A) sweat glands
B) sebaceous glands
C) Meibomian glands
D) ceruminous glands

B) sebaceous glands

The dermis ________.
A) is an avascular connective tissue layer
B) has two layers
C) lacks sensory corpuscles and glands
D) is where melanocytes are found

B) has two layers

Which muscles attached to the hair follicles cause goose bumps?
A) arrector integument
B) arrector pili
C) levator folliculi
D) arrector folliculi

B) arrector pili

If a splinter penetrated the skin into the second epidermal layer of the sole of the foot, which cells would be damaged?
A) granulosum
B) basale
C) lucidum
D) spinosum

C) lucidum

Which of the following cutaneous receptors is specialized for the reception of touch or light pressure?
A) Meissner's corpuscles
B) Pacinian corpuscles
C) free nerve endings
D) Krause's end bulbs

A) Meissner's corpuscles

Melanocytes ________.
A) are spidery-shaped cells in contact with cells in the stratum basale
B) are involved in the immune system
C) are involved with the nervous system
D) work their way up to the surface just like the keratinocytes

A) are spidery-shaped cells in contact with cells in the stratum basale

Which statement correctly explains why hair appears the way it does?
A) Kinky hair has flat, ribbonlike hair shafts.
B) Perfectly round hair shafts result in wavy hair.
C) Air bubbles in the hair shaft cause straight hair.
D) Gray hair is the result of hormonal action altering the chemical composition of melanin.

A) Kinky hair has flat, ribbonlike hair shafts.

Sudoriferous glands vary in distribution over the surface of the body. Which of the following is correct?
A) Eccrine are the most numerous, being found primarily in the axillary regions.
B) Apocrine glands are larger than eccrine, and empty secretions directly to the surface of the skin.
C) Ceruminous glands secrete cerumen, which is thought to deter insects.
D) Mammary glands are not considered a modified sweat gland.

C) Ceruminous glands secrete cerumen, which is thought to deter insects.

Although the integument is a covering, it is by no means simple, and some of its functions include ________.
A) the dermis providing the major mechanical barrier to chemicals, water, and other external substances
B) resident macrophage-like cells whose function is to ingest antigenic invaders and present them to the immune system
C) cooling the body by increasing the action of sebaceous glands during high-temperature conditions
D) epidermal blood vessels serving as a blood reservoir

B) resident macrophage-like cells whose function is to ingest antigenic invaders and present them to the immune system

The function of the root hair plexus is to ________.
A) serve as a source for new epidermal cells for hair growth after the resting stage has passed
B) bind the hair root to the dermis
C) cause apocrine gland secretion into the hair follicle
D) allow the hair to assist in touch sensation

D) allow the hair to assist in touch sensation

Vernix caseosa is a ________.
A) substance contributing to acne during adolescence
B) whitish material produced by fetal sebaceous glands
C) coat of fine, downy hair on the heads of balding men
D) cheesy-looking sudoriferous secretion on the skin of newborns

B) whitish material produced by fetal sebaceous glands

The ________ gland is a modified sudoriferous gland that secretes wax.
A) eccrine
B) apocrine
C) ceruminous
D) mammary

C) ceruminous

Nutrients reach the surface of the skin (epidermis) through the process of ________.
A) absorbing materials applied to the surface layer of the skin
B) utilizing the products of merocrine glands to nourish the epidermis
C) filtration
D) diffusing through the tissue fluid from blood vessels in the dermis

D) diffusing through the tissue fluid from blood vessels in the dermis

The reason the hypodermis acts as a shock absorber is that ________.
A) it is located just below the epidermis and protects the dermis from shock
B) it has no delicate nerve endings and can therefore absorb more shock
C) the major part of its makeup is adipose, which serves as an effective shock absorber
D) the cells that make up the hypodermis secrete a protective mucus

C) the major part of its makeup is adipose, which serves as an effective shock absorber

The epidermis is responsible for protecting the body against invasion of bacteria and other foreign agents primarily because it is composed of ________.
A) stratified columnar epithelium
B) three layers of keratinized cells only
C) four different cell shapes found in five distinct layers, each cell shape with a special function
D) a tough layer of connective tissue

C) four different cell shapes found in five distinct layers, each cell shape with a special function

Keratinocytes are an important epidermal cell because ________.
A) they produce a fibrous protein that gives the skin much of its protective properties
B) they are able to transform from living cells to plasma membranes and still function
C) they are able to reproduce sporadically as needed
D) they are a powerful defense against damaging UV rays

A) they produce a fibrous protein that gives the skin much of its protective properties

Melanocytes and keratinocytes work together in protecting the skin from UV damage when keratinocytes ________.
A) provide the melanocyte with a protective shield against abrasion
B) accumulate the melanin granules on their superficial portion, forming a UV-blocking pigment layer
C) maintain the appropriate pH in order for the melanocyte to synthesize melanin granules
D) maintain the appropriate temperature so the product of the melanocyte will not denature

B) accumulate the melanin granules on their superficial portion, forming a UV-blocking pigment layer

The epidermis consists of five layers of cells, each layer with a distinct role to play in the health, well-being, and functioning of the skin. Which of the following layers is responsible for cell division and replacement?
A) stratum corneum
B) stratum granulosum
C) stratum basale
D) stratum lucidum

C) stratum basale

The integumentary system is protected by the action of cells that arise from bone marrow and migrate to the epidermis. Which of the following cells serve this function?
A) cells found in the stratum spinosum
B) macrophages called Langerhans' cells
C) keratinocytes, because they are so versatile
D) Merkel cells

B) macrophages called Langerhans' cells

Water loss through the epidermis could cause a serious threat to health and well-being. Which of the following protects us against excessive water loss through the skin?
A) Lamellated granules of the cells of the stratum granulosum, a glycolipid that is secreted into extracellular spaces.
B) The size and shape of the cells that make up the stratum spinosum, as well as the thick bundles of intermediate filaments.
C) The dermis is the thickest portion of the skin and water cannot pass through it.
D) Fat associated with skin prevents water loss.

A) Lamellated granules of the cells of the stratum granulosum, a glycolipid that is secreted into extracellular spaces.

The dermis is a strong, flexible connective tissue layer. Which of the following cell types are likely to be found in the dermis?
A) goblet cells, parietal cells, and Kupffer cells
B) monocytes, reticulocytes, and osteocytes
C) fibroblasts, macrophages, and mast cells
D) osteoblasts, osteoclasts, and epithelial cells

C) fibroblasts, macrophages, and mast cells

The dermis has two major layers; which of the following constitutes 80% of the dermis and is responsible for the tension lines in the skin?
A) the reticular layer
B) the subcutaneous layer
C) the hypodermal layer
D) the papillary layer

A) the reticular layer

Despite its apparent durability, the dermis is subject to tearing. How might a person know that the dermis has been stretched and/or torn?
A) Because the pain is acute due to the large number of Meissner's corpuscles.
B) The appearance of visible, silvery-white scars is an indication of stretching of the dermis.
C) The blood vessels in the dermis rupture and the blood passes through the tissue, causing "black and blue marks."
D) The stretching causes the tension lines to disappear.

B) The appearance of visible, silvery-white scars is an indication of stretching of the dermis.

The papillary layer of the dermis is connective tissue heavily invested with blood vessels. The superficial surface has structures called:
A) dermal papillae.
B) hair follicles.
C) ceruminous glands.
D) reticular papillae.

A) dermal papillae.

The design of a person's epidermal ridges is determined by the manner in which the papillae rest upon the dermal ridges to produce the specific pattern known as handprints, footprints, and fingerprints. Which of the following statements is true regarding these prints or ridges?
A) Every human being has the same pattern of ridges.
B) They are genetically determined, therefore unique to each person.
C) Because we are constantly shedding epithelial cells, these ridges are changing daily.
D) Identical twins do not have the same pattern of ridges.

B) They are genetically determined, therefore unique to each person.

Which of the following statements indicates the way in which the body's natural defenses protect the skin from the effects of UV damage?
A) The skin is protected by the synthesis of three pigments that contribute to the skin's color.
B) Carotene, which accumulates in the stratum corneum and hypodermal adipose tissue, is synthesized in large amounts in the presence of sunlight.
C) The skin is protected by increasing the number of Langerhans' cells, which help to activate the immune system.
D) Prolonged exposure to the sun induces melanin dispersion, which in turn acts as a natural sunscreen.

D) Prolonged exposure to the sun induces melanin dispersion, which in turn acts as a natural sunscreen.

Changes in the color of skin are often an indication of a homeostatic imbalance. Which of the following changes would suggest that a patient is suffering from Addison's disease?
A) The skin takes on a bronze or metallic appearance.
B) Black-and-blue marks become evident for no apparent cause.
C) The skin appears to have an abnormal, yellowish tint.
D) It is impossible to suggest Addison's disease from an inspection of a person's skin.

A) The skin takes on a bronze or metallic appearance.

A Langerhans' cell is a ________.
A) specialized squamous epithelial cell
B) specialized phagocytic cell
C) specialized nerve cell
D) specialized melanocyte

B) specialized phagocytic cell

The most important factors influencing hair growth are ________.
A) sex and hormones
B) age and glandular products
C) the size and number of hair follicles
D) nutrition and hormones

D) nutrition and hormones

Which of the following statements best describes what fingernails actually are?
A) Fingernails are a modification of the epidermis.
B) Fingernails are derived from osseous tissue.
C) Fingernails are extensions of the carpal bones.
D) Fingernails are a separate tissue from the skin, formed from a different embryonic layer.

A) Fingernails are a modification of the epidermis.

Sudoriferous (sweat) glands are categorized as two distinct types. Which of the following are the two types of sweat glands?
A) sebaceous and merocrine
B) mammary and ceruminous
C) eccrine and apocrine
D) holocrine and mammary

C) eccrine and apocrine

The composition of the secretions of the eccrine glands is ________.
A) primarily uric acid
B) 99% water, sodium chloride, trace amounts of wastes, and vitamin C
C) fatty substances, proteins, antibodies, and trace amounts of minerals and vitamins
D) metabolic wastes

B) 99% water, sodium chloride, trace amounts of wastes, and vitamin C

Apocrine glands, which begin to function at puberty under hormonal influence, seem to play little role in thermoregulation. Where would we find these glands in the human body?
A) in all body regions and buried deep in the dermis
B) beneath the flexure lines in the body
C) in the axillary and anogenital area
D) in the palms of the hands and soles of the feet

C) in the axillary and anogenital area

The sebaceous glands are simple alveolar glands that secrete a substance known as sebum. The secretion of sebum is stimulated ________.
A) by high temperatures
B) when the air temperature drops
C) by hormones, especially androgens
D) as a protective coating when one is swimming

C) by hormones, especially androgens

In addition to protection (physical and chemical barrier), the skin serves other functions. Which of the following is another vital function of the skin?
A) It converts modified epidermal cholesterol to a vitamin D precursor important to calcium metabolism.
B) It aids in the transport of materials throughout the body.
C) The cells of the epidermis store glucose as glycogen for energy.
D) It absorbs vitamin C so that the skin will not be subject to diseases.

A) It converts modified epidermal cholesterol to a vitamin D precursor important to calcium metabolism.

Burns are devastating and debilitating because of loss of fluids and electrolytes from the body. How do physicians estimate the extent of burn damage associated with such dangerous fluid loss?
A) by measuring urinary output and fluid intake
B) by observing the tissues that are usually moist
C) through blood analysis
D) by using the "rule of nines"

D) by using the "rule of nines"

What is the first threat to life from a massive third-degree burn?
A) infection
B) catastrophic fluid loss
C) unbearable pain
D) loss of immune function

B) catastrophic fluid loss

Male pattern baldness has a genetic switch that turns on in response to ________.
A) age
B) size
C) weight
D) male hormones

D) male hormones

Eyebrow hairs are always shorter than hairs on your head because ________.
A) they grow much slower
B) eyebrow follicles are only active for a few months
C) the vascular supply of the eyebrow follicle is one-tenth that of the head hair follicle
D) hormones in the eyebrow follicle switch the growth off after it has reached a predetermined length

B) eyebrow follicles are only active for a few months

Which cell functions as part of the immune system:

a. keratinocyte
b. melanocyte
c. Langerhans
d. Merkel cell

c. Langerhans

The epidermis provides a physical barrier due largely to the presence of:
a. melanin
b. carotene
c. collagen
d. keratin

keratin

The skin color is determined by:

a. the amount of blood
b. the pigments
c. oxygenation level of the blood
d. all of these

d. all of these

The sensations of touch and pressure are picked up by receptors located in:
a. the stratum germinatvum
b. the dermis
c. the hypodermis
d. the stratum corneum

b. the dermis

Which is not true about the papillary layer of the dermis

a. it produces the pattern for fingerprints
b. it is most responsible for the toughness of the skin
c. it contains nerve endings that respond to stimuli d. it is highly vascular

b. it is most responsible for the toughness of the skin

Skin surface markings that reflect points of tight dermal attachment to underlying tissues are called:
a. tension lines
b. papillary ridges
c. flexure lines
d. epidermal papillae

c. flexure lines

Which of the following is not an epidermal derivative: a. hair b. sweat gland c. sensory receptor d. sebaceous gland

c. sensory

An arrector pili muscle: a. is associated each sweat gland b. can cause a hair to stand up straight c. enables each hair to be stretched when wet d. provides new cells for continued growth of its associated hair

b. can cause a hair to stand up

The product of this type of sweat gland includes protein and lipid substances that become odoriferous as a result of bacterial action: a. apocrine gland b. Eccrine gland c. sebaceous gland d. pancreatic gland

a. apocrine gland

Sebum: a. lubricates the surface of the skin and hair b. consists of dead cells and fatty substances c. in excess may cause seborrhea d. all of these

d. all of these

The rule of nines is helpful clinically in: a. diagnosing skin cancer b. estimating the extent of a burn c estimating how serious a cancer is d. preventing acne

b. estimating the extent of a burn

Which epidermal cells are also called prickle cells? Which contain keratohyaline and lamellated granules?

Stratum Spinosum, Stratum granulosum

Burns are devastating and debilitating because of loss of fluids and electrolytes from the body. How do physicians estimate the extent of burn damage associated with such dangerous fluid loss?

a by observing the tissues that are usually moist
b through blood analysis
c by using the "rule of nines"
d by measuring urinary output and fluid intake

by using the "rule of nines"

The white crescent portion of the nail is called the ________.

lunula

Sudoriferous glands vary in distribution over the surface of the body. Which of the following is correct?

a. Apocrine glands are larger than eccrine, and empty secretions directly to the surface of the skin.
b Eccrine are the most numerous, being found primarily in the axillary regions.
c. Mammary glands are not considered a modified sweat gland.
d. Ceruminous glands secrete cerumen, which is thought to deter insects.

Ceruminous glands secrete cerumen, which is thought to deter insects.

Which of the following cutaneous receptors is specialized for the reception of touch or light pressure?


Free nerve endings
Pacinian corpuscles
Meissner's corpuscles
Krause's end bulbs

Meissner's corpuscles

Which statement correctly explains why hair appears the way it does?

a Gray hair is the result of hormonal action altering the chemical composition of melanin.
b Perfectly round hair shafts result in wavy hair.
c Kinky hair has flat, ribbonlike hair shafts.
d Air bubbles in the hair shaft cause straight hair.

Kinky hair has flat, ribbonlike hair shafts.

The dermis is rich in blood vessels and nerve fibers.

True

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