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5 Written Questions

5 Matching Questions

  1. Main Output of Basal Ganglia
  2. slow speed of movement
  3. Removes inhibition to the thalamus
  4. Pathologically there is loss of dopaminergic neurons in the Substantia nigra pars compacta
  5. Abnormal positions of the body, head, or limbs
  1. a Thalamus
  2. b Dystonia
  3. c Parkinson's Disease
  4. d Direct pathway
  5. e Bradykinesia

5 Multiple Choice Questions

  1. Parkinson's Disease
  2. Ballismus
  3. Rigidity
  4. Hyperkinesia
  5. Indirect Pathway

5 True/False Questions

  1. Twisting movements of limbs, face, and trunkAthetosis


  2. -Gradual and progressive behavioral, cognitive symptoms and choreic movements beginning in the forth or fifth decade of life
    -Death occurs within 10 to 20 years
    -Inherited as an autosomal dominant disorder
    -The defective gene is located in the short arm of chromosome 4 and encodes for the protein huntingtin
    -The gene includes multiple tandem repeats of the trinucleotide CAG encoding glutamine


  3. 1. Globus pallidus - internal segment
    2. Substantia nigra pars reticulata
    Nuclei of the basal ganglia that provide the output information


  4. -Abnormal movements of the proximal limb muscles
    -The amplitude of the movement is larger than in choreic movements
    -It is most common due to a lacunar infarct of the contralateral subthalamic nucleus
    -Other causes are hemorrhages, tumors, and inflammatory diseases


  5. Caudate nucleus


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