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5 Written Questions

5 Matching Questions

  1. Pathologically there is loss of dopaminergic neurons in the Substantia nigra pars compacta
  2. -Gradual and progressive behavioral, cognitive symptoms and choreic movements beginning in the forth or fifth decade of life
    -Death occurs within 10 to 20 years
    -Inherited as an autosomal dominant disorder
    -The defective gene is located in the short arm of chromosome 4 and encodes for the protein huntingtin
    -The gene includes multiple tandem repeats of the trinucleotide CAG encoding glutamine
  3. 1. Globus pallidus - internal segment
    2. Substantia nigra pars reticulata
  4. Main Output of Basal Ganglia
  5. -Motor control loop
    -Eye movement loop
    -Cognitive function loop
    -Limbic loop
  1. a Thalamus
  2. b Parkinson's Disease
  3. c Nuclei of the basal ganglia that provide the output information
  4. d Basal Ganglia Loops
  5. e Huntington's Disease

5 Multiple Choice Questions

  1. Hypokinesia
  2. Athetosis
  3. Symptoms or signs in basal ganglia damage
  4. Ballismus
  5. Rigidity

5 True/False Questions

  1. Putamen
    Globus Pallidus
    Lenticular nucleus


  2. Caudate nucleus
    Globus Pallidus
    Subthalamic nucleus
    Substantia nigra
    Nucleus accumbens
    Symptoms or signs in basal ganglia damage


  3. Continuous involuntary movements of the face, limbs or trunkChorea


  4. -Resting tremor
    -Bradykinesia - Slowness of movement
    -Rigidity of extremities
    -Minimal facial expression - masked facies
    -Shuffling gait with decreased associated movements such as arm swinging
    -In some cases these symptoms are also associated with dementia
    Parkinson's Disease


  5. -Control the initiation of movement
    -Control the smooth transition between 2 consecutive movements
    Basal Ganglia Function


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