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5 Written questions

5 Matching questions

  1. Effects of anaphylaxis
  2. Cold hemagglutinin disease‐
  3. Treatment for anaphylaxis
  4. Drug allergy: Induction drugs
  5. Multiple myeloma
  1. a Proliferation of single clone B‐ lymphocytes->immune complex deposition
  2. b Mast cell/basophil degranulation->release of
    histamine, prostaglandins, & leukotrienes->vasodilation & ↑d capillary permeability->hypotension, bronchoconstriction & CV
    collapse
  3. c Barbs‐ rare, severe
    Propofol- egg lecithin emulsion, most common, high incidence of bronchospasm
  4. d O2, IV fluids, epinephrine, H1 antagonists, steroids
  5. e IgM binds erythrocytes when cold->hemolysis, compliment activation, acrocyanosis, Raynaud's, purpura, gangrene, nephritis

5 Multiple choice questions

  1. Release of vasoactive amines
  2. Similar to anaphylaxis
  3. Inability to form any class of antibodies (absent mature B‐lymphocytes)->recurrent bacterial infections
  4. Hereditary angioedema
  5. Airway‐ macroglossia
    CV‐ conduction disturbance, RHF
    Renal‐ nephrotic syndrome
    Nerves‐ autonomic neuropathy, nerve compression

5 True/False questions

  1. Drug allergy: LAsHalothane hepatitis- trifluoroacetyl halide metabolites + hepatic microsomal proteins->neoantigens
    Sevo doesn't produce oxidative halide metabolites

          

  2. Drug toxicityAntigen-antibody, hypotension, bronchospasm, urticaria, unpredictable severity, prior exposure, rapid onset, not dose related, low incidence

          

  3. IgM‐Mast cells, Anaphylaxis and allergy

          

  4. Anaphylaxis primary exposureMassive degranulation of mast cells & basophils

          

  5. Drug allergy: VAsHalothane hepatitis- trifluoroacetyl halide metabolites + hepatic microsomal proteins->neoantigens
    Sevo doesn't produce oxidative halide metabolites

          

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