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5 Written questions

5 Matching questions

  1. Waldenstrom's macroglobulinemia
  2. Drug allergy: latex
  3. X‐linked agammaglobulinemia‐
  4. Drug allergy: abx
  5. Drug allergy
  1. a Inability to form any class of antibodies (absent mature B‐lymphocytes)->recurrent bacterial infections
  2. b Neoplastic proliferation of IgM secreting plasma cell->hyper‐ viscosity, infiltration of liver, spleen, lungs, & bone marrow
  3. c ↑d incidence in medical personnel (15% in
    anesthesiologists)
    Patients w/ multiple surgeries, fruit (banana)
    allergies & spina bifida
    Potential for delayed reaction (>30 minutes)
  4. d Vanco‐ life threatening anaphylactic &
    anaphylactoid (red man syndrome) reactions
    PCN‐ most common cause of fatal anaphylaxis (structurally r/t cephalosporins-> theoretical ↑d risk of allergy
  5. e Antigen-antibody, hypotension, bronchospasm, urticaria, unpredictable severity, prior exposure, rapid onset, not dose related, low incidence

5 Multiple choice questions

  1. Rare, accounts for 1% of adverse reactions to locals
    Ester based->PABA
    Preservatives (methylparaben, propylparaben) similar to PABA
    No proven cross-reactivity between ester & amides
  2. Abnormal proteins agglutinate in response to cold
    Cryoglobulinemia
    Cold hemagglutinin disease
  3. Capillary permeability
    Bronchoconstriction
    Negative inotropy
    Coronary artery vasoconstriction
  4. Hereditary angioedema
  5. Anaphylaxis‐ IgE mediated reaction
    Rhinitis‐ IgE mediated
    Asthma
    Food & drug allergies

5 True/False questions

  1. Dosing for epinephrine for shock but w/ pressure1 mg 1:1000
    0.01 mg/kg IM
    Max 0.5 mg in adult
    Max 0.3 mg in child

          

  2. Hereditary angioedemaEmotional stress triggers 30-40% of attacks

          

  3. Platelet activating factor effectsRelease of vasoactive amines

          

  4. Drug allergy: crossmatched blood↑d incidence in medical personnel (15% in
    anesthesiologists)
    Patients w/ multiple surgeries, fruit (banana)
    allergies & spina bifida
    Potential for delayed reaction (>30 minutes)

          

  5. IgA‐Lysis of bacterial cell walls

          

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