Thiaminase-containing Plants

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Created by:

FeralAtheist  on October 12, 2011

Subjects:

toxicology

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Thiaminase-containing Plants

What plants contain thiaminase?
Brackenfern (Pteridium)
Horsetail (Equisetum)
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Definitions

What plants contain thiaminase? Brackenfern (Pteridium)
Horsetail (Equisetum)
What species are primarily affected by Brackenfern (Pteridium)? Horses and Cattle
What is the toxic principle of Brackenfern (Pteridium) in cattle? Ptaquiloside
What are the signs/syndromes associated with ptaquiloside toxicosis in cattle? bladder cancer - bovine enzootic hematuria
bone marrow suppression - radiomimetic dz
Ddx of brackenfern in cattle? anaplasmosis, leptospirosis, moldy sweet clover, septicemia
What is one important treatment of brackenfern poisoning in cattle? blood transfusion
What is the toxic principle of brackenfern (pteridium) in horses? thiaminase
What is the mechanism of action of thiaminase in the horse? decreased absorption of thiamine, leading to decreased thiamine in the blood and decreased ATP
What is a key clinical sign of thiaminase/brackenfern toxicosis in the horse? CNS dysfuction = bracken staggers
What is the toxic principle of Horsetail (Equisetum)? Thiaminase
What is a treatment for thiaminase toxicosis in horses? thiamine

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