Term Quiz 3

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jessmh33  on October 14, 2011

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Term Quiz 3

Agonist
An agent that binds to receptors and enhances or mimics the effect of a natural neurotransmitter.
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Definitions

Agonist An agent that binds to receptors and enhances or mimics the effect of a natural neurotransmitter.
Metabotropic Receptors Type of neurotransmitter receptor that contains a neurotransmitter binding site but lacks an ion channel as part of its structure.
SSRls (Selective Serotonin Reuptake Inhibitors Drugs that provide relief from some forms of depression.
Postsynaptic Potential Change in membrane voltage as ions flow through opened channels.
EPSP (Excitatory Postsynaptic Potential) Depolarizing postsynaptic potential.
Action Potentials Allow communication over long distances within the body.
Electrochemical Gradient Concentration (chemical) difference plus an electrical difference which allow specific ions to move across the plasma membrane.
Catecholamines Include an amino acid group and a catechol ring; synthesized from the amino acid tyrosine.
Voltage Gated Channel Opens in response to a change in membrane potential (voltage)
Anterior Root Conduct nerve impulses from the CNS to effectors (muscles and glands)
Decremental Conduction Mode of travel which graded potentials die out as they spread along the membrane.
Leak Ion Channel Gates which randomly alternate between open and closed positions.
Excitotoxicity Caused by high level of glutamate in the interstitial fluid of the CNS.
Posterior Root Contain only sensory axons; conduct nerve impulses from sensory receptors in the skin, muscles, and internal organs into the CNS.
C Fibers Smallest diameter axons; unmyelinated; longest absolute refractory period.
IPSP (Inhibitory Postsynaptic Potential) Hyperpolarizing Postsynaptic Potential.
Presynaptic Neuron Nerve cell that carries a nerve impulse toward a synapse.
Postsynaptic Neuron Cell that carries a nerve impulse away from a synapse or an effector cell that responds to the impulse at the synapse.
Summation Process by which graded potentials add together.
Temporal Summation Summation of postsynaptic potentials in response to stimuli that occur at the same location in the membrane of the postsynaptic cell but at different times.
Graded Potential Small deviation from the membrane potential that makes the membrane either more polarized or less polarized.
Ionotropic Receptors Type of neurotransmitter receptor that contains a neurotransmitter binding site and an ion channel.
Spinal Tap Local anesthetic given as a long hollow needle is inserted into the subarachnoid space to withdraw cerebrospinal fluid for diagnostic purposes.
Threshold An action potential occurs in the membrane of the axon of a neuron when depolarization reaches a certain level.
All-or-none Principle An action potential is generated in response to a threshold stimulus but does not form when there is a subthreshold stimulus.
Refractory Period The period of time after an action potential in an excited cell cannot generate another action potential in response to a normal threshold stimulus.
Anterior Gray Horn Contain somatic motor nuclei.
Synaptic Cleft Space of 20-50 mm filled with interstitial fluid which separate chemical synapses.
Local Anesthetics Drugs that block pain and other somatic sensations.
Saltatory Conduction Special mode of action potential propagation that occurs along myelinated axon.
Antagonist An agent that binds to and blocks neurotransmitter receptors.
Nitric Oxide Important excitatory neurotransmitter secreted in the brain, spinal cord, adrenal glands, and nerves to the penis; contains single N atoms.
Neural Divergence Permits one presynaptic neuron to influence several postsynaptic neurons at the same time.
Neural Convergence Several presynaptic neurons synapse with a single postsynaptic neuron.
Spatial Summation Summation of post-synaptic potentials in response to stimuli that occur at different locations in the membrane of a postsynaptic cell at the same time.
Hyperpolarizing When the response makes the membrane more polarized.
A Fibers Largest diameter axons; myelinated; brief absolute refractory period, conduct nerve impulses.
Posterior Gray Horns Contains cell bodies and axons of interneurons as well as axons of incoming sensory neurons.
Plasticity The capability to change based on experience.
GABA (Gamma Aminobutyric Acid) found only in the CNS; most common inhibitory neurotransmitter.
Glutamate Amino acid which is a neurotransmitter in the CNS.
Acetylcholine Best-studied neurotransmitter which is released by many PNS neurons and some CNS neurons.
Depolarizing When the response makes a membrane less polarized.
Ligand Gated Channel Opens and closes in response to the binding of a chemical stimulus.

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