5 Written questions
5 Matching questions
- end plate potential (EPP)
- end plates
- SNAPs (soluble NSF-attachments proteins)
- a partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.
- b Involved in priming synaptic vesicles for release. Work by regulating the assembly of SNARE proteins.
- c a SNARE protein on the surface of the synaptic vesicle. Binds Ca++ at concentrations similar to those required to trigger vesicle fusion, basically allowing it to act as a Ca++ sensor and triggering fusion.
- d membrane potential on an end plate large enough to trigger an action potential
- e neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber
5 Multiple choice questions
- an ATPase involved in priming synaptic vesicle for fusion
- chemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.
- Work by allowing ionic current to flow PASSIVELY through the gap junction pores from one neuron to the next. Very fast transmission.
- Make electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.
- A neurotransmitter found primarily at neuromuscular junctions of the striated muscles and in the visceral motor system. Involved in muscle contraction and heart rate increases.
5 True/False questions
mini end plate potentials (MEPPS) → membrane potential on an end plate large enough to trigger an action potential
clathrin → a very important protein involved in endocyctotic budding of vesicles from the plasma membrane. Assemble together (by polymerization) to form membrane coats during the budding of the phase synaptic vesicle cycle.
co-transmitters → chemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.
synapsin → reversibly binds to synaptic vesicles and may cross link vesicle to actin filaments in the cytoskeleton to keep the vesicles tethered within the reserve pool.
synaptic vesicle cycle → a V-SNARE protein that binds to the synaptic vesicle before exocytosis