5 Written questions
5 Matching questions
- Electrical synapses
- a chemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.
- b a SNARE protein on the surface of the synaptic vesicle. Binds Ca++ at concentrations similar to those required to trigger vesicle fusion, basically allowing it to act as a Ca++ sensor and triggering fusion.
- c Work by allowing ionic current to flow PASSIVELY through the gap junction pores from one neuron to the next. Very fast transmission.
- d partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.
- e How neurotransmitters are referred to when two or more of them are present in the same nerve terminal.
5 Multiple choice questions
- Make electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.
- a very important protein involved in endocyctotic budding of vesicles from the plasma membrane. Assemble together (by polymerization) to form membrane coats during the budding of the phase synaptic vesicle cycle.
- neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber
- an ATPase involved in priming synaptic vesicle for fusion
- a protein that causes the final pinching-off of the membrane that completes the production of coated vesicles in the synaptic vesicle cycle.
5 True/False questions
synaptic vesicle cycle → a V-SNARE protein that binds to the synaptic vesicle before exocytosis
large dense-core vesicles → Vesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.
synaptobrevin → a V-SNARE protein that binds to the synaptic vesicle before exocytosis
mini end plate potentials (MEPPS) → membrane potential on an end plate large enough to trigger an action potential
CamKII → a very important protein involved in endocyctotic budding of vesicles from the plasma membrane. Assemble together (by polymerization) to form membrane coats during the budding of the phase synaptic vesicle cycle.