5 Written Questions
5 Matching Questions
- end plates
- small clear-core vesicle
- Electrical synapses
- a Work by allowing ionic current to flow PASSIVELY through the gap junction pores from one neuron to the next. Very fast transmission.
- b Vesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.
- c partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.
- d reversibly binds to synaptic vesicles and may cross link vesicle to actin filaments in the cytoskeleton to keep the vesicles tethered within the reserve pool.
- e neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber
5 Multiple Choice Questions
- Package neuropeptides. These vesicles are much larger in size than small clear-core vesicles. Made in the soma and shipped down to the terminal via fast axonal transport.
- Make electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.
- A neurotransmitter found primarily at neuromuscular junctions of the striated muscles and in the visceral motor system. Involved in muscle contraction and heart rate increases.
- a very important protein involved in endocyctotic budding of vesicles from the plasma membrane. Assemble together (by polymerization) to form membrane coats during the budding of the phase synaptic vesicle cycle.
- a V-SNARE protein that binds to the synaptic vesicle before exocytosis
5 True/False Questions
Neurotransmitters → How neurotransmitters are referred to when two or more of them are present in the same nerve terminal.
CamKII → a kinase that phosphorylates synapsin and causes it to let go of the synaptic vesicles it is holding in the reserve pool
NSF (NEM-sensitive fusion protein) → an ATPase involved in priming synaptic vesicle for fusion
co-transmitters → chemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.
hsc-70 → a kinase that phosphorylates synapsin and causes it to let go of the synaptic vesicles it is holding in the reserve pool