5 Written questions
5 Matching questions
- synaptic vesicle cycle
- small clear-core vesicle
- Electrical synapses
- a with the aid of auxilin, this removes the clathrin coating so that the vesicle can move onto other phases of recycling
- b Work by allowing ionic current to flow PASSIVELY through the gap junction pores from one neuron to the next. Very fast transmission.
- c recycling process for synaptic vesicle. Process takes about 1 minute.
- d chemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.
- e Vesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.
5 Multiple choice questions
- make up EPPS and correspond to the release of just one or two vesicle. Small, happen spontaneously, and cannot trigger an AP.
- a V-SNARE protein that binds to the synaptic vesicle before exocytosis
- neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber
- membrane potential on an end plate large enough to trigger an action potential
- an ATPase involved in priming synaptic vesicle for fusion
5 True/False questions
acetylcholine (ACh) → a very important protein involved in endocyctotic budding of vesicles from the plasma membrane. Assemble together (by polymerization) to form membrane coats during the budding of the phase synaptic vesicle cycle.
curare → a kinase that phosphorylates synapsin and causes it to let go of the synaptic vesicles it is holding in the reserve pool
SNAPs (soluble NSF-attachments proteins) → Involved in priming synaptic vesicles for release. Work by regulating the assembly of SNARE proteins.
dynamin → a protein that causes the final pinching-off of the membrane that completes the production of coated vesicles in the synaptic vesicle cycle.
CamKII → partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.