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5 Written questions

5 Matching questions

  1. Neurotransmitters
  2. synaptotagmin
  3. co-transmitters
  4. curare
  5. Electrical synapses
  1. a chemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.
  2. b a SNARE protein on the surface of the synaptic vesicle. Binds Ca++ at concentrations similar to those required to trigger vesicle fusion, basically allowing it to act as a Ca++ sensor and triggering fusion.
  3. c Work by allowing ionic current to flow PASSIVELY through the gap junction pores from one neuron to the next. Very fast transmission.
  4. d partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.
  5. e How neurotransmitters are referred to when two or more of them are present in the same nerve terminal.

5 Multiple choice questions

  1. Make electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.
  2. a very important protein involved in endocyctotic budding of vesicles from the plasma membrane. Assemble together (by polymerization) to form membrane coats during the budding of the phase synaptic vesicle cycle.
  3. neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber
  4. an ATPase involved in priming synaptic vesicle for fusion
  5. a protein that causes the final pinching-off of the membrane that completes the production of coated vesicles in the synaptic vesicle cycle.

5 True/False questions

  1. synaptic vesicle cyclea V-SNARE protein that binds to the synaptic vesicle before exocytosis

          

  2. large dense-core vesiclesVesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.

          

  3. synaptobrevina V-SNARE protein that binds to the synaptic vesicle before exocytosis

          

  4. mini end plate potentials (MEPPS)membrane potential on an end plate large enough to trigger an action potential

          

  5. CamKIIa very important protein involved in endocyctotic budding of vesicles from the plasma membrane. Assemble together (by polymerization) to form membrane coats during the budding of the phase synaptic vesicle cycle.

          

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