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5 Written questions

5 Matching questions

  1. co-transmitters
  2. end plate potential (EPP)
  3. synaptotagmin
  4. synaptic vesicle cycle
  5. end plates
  1. a membrane potential on an end plate large enough to trigger an action potential
  2. b neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber
  3. c How neurotransmitters are referred to when two or more of them are present in the same nerve terminal.
  4. d a SNARE protein on the surface of the synaptic vesicle. Binds Ca++ at concentrations similar to those required to trigger vesicle fusion, basically allowing it to act as a Ca++ sensor and triggering fusion.
  5. e recycling process for synaptic vesicle. Process takes about 1 minute.

5 Multiple choice questions

  1. make up EPPS and correspond to the release of just one or two vesicle. Small, happen spontaneously, and cannot trigger an AP.
  2. Make electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.
  3. reversibly binds to synaptic vesicles and may cross link vesicle to actin filaments in the cytoskeleton to keep the vesicles tethered within the reserve pool.
  4. Package neuropeptides. These vesicles are much larger in size than small clear-core vesicles. Made in the soma and shipped down to the terminal via fast axonal transport.
  5. partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.

5 True/False questions

  1. CamKIIa kinase that phosphorylates synapsin and causes it to let go of the synaptic vesicles it is holding in the reserve pool

          

  2. SNAPs (soluble NSF-attachments proteins)an ATPase involved in priming synaptic vesicle for fusion

          

  3. hsc-70with the aid of auxilin, this removes the clathrin coating so that the vesicle can move onto other phases of recycling

          

  4. Neurotransmitterschemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.

          

  5. syntaxin and SNAP-25Work by allowing ionic current to flow PASSIVELY through the gap junction pores from one neuron to the next. Very fast transmission.

          

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