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5 Written questions

5 Matching questions

  1. Gap Junctions
  2. synapsin
  3. end plate potential (EPP)
  4. small clear-core vesicle
  5. dynamin
  1. a membrane potential on an end plate large enough to trigger an action potential
  2. b reversibly binds to synaptic vesicles and may cross link vesicle to actin filaments in the cytoskeleton to keep the vesicles tethered within the reserve pool.
  3. c Make electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.
  4. d Vesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.
  5. e a protein that causes the final pinching-off of the membrane that completes the production of coated vesicles in the synaptic vesicle cycle.

5 Multiple choice questions

  1. Involved in priming synaptic vesicles for release. Work by regulating the assembly of SNARE proteins.
  2. make up EPPS and correspond to the release of just one or two vesicle. Small, happen spontaneously, and cannot trigger an AP.
  3. an ATPase involved in priming synaptic vesicle for fusion
  4. a SNARE protein on the surface of the synaptic vesicle. Binds Ca++ at concentrations similar to those required to trigger vesicle fusion, basically allowing it to act as a Ca++ sensor and triggering fusion.
  5. partially blocks post synaptic ACh receptors when placed in the extracellular medium. Used to study EPPs and MEPPs.

5 True/False questions

  1. large dense-core vesiclesVesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.

          

  2. Neurotransmitterschemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.

          

  3. clathrina kinase that phosphorylates synapsin and causes it to let go of the synaptic vesicles it is holding in the reserve pool

          

  4. end platesneuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber

          

  5. syntaxin and SNAP-25T-SNARE proteins embedded to the pre-synapatic membrane; attach to synaptic vesicles for vesicle fusion

          

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