5 Written Questions
5 Matching Questions
- Gap Junctions
- syntaxin and SNAP-25
- a with the aid of auxilin, this removes the clathrin coating so that the vesicle can move onto other phases of recycling
- b T-SNARE proteins embedded to the pre-synapatic membrane; attach to synaptic vesicles for vesicle fusion
- c a SNARE protein on the surface of the synaptic vesicle. Binds Ca++ at concentrations similar to those required to trigger vesicle fusion, basically allowing it to act as a Ca++ sensor and triggering fusion.
- d chemical agents acting as messengers between the communicating neurons. Released from vesicle when the is a large Ca++ influx into the cell. How many are released depends on how much Ca++ enters the terminal.
- e Make electrical synapses possible. Consists of hexameric subunits made up of subunits called connexons.
5 Multiple Choice Questions
- How neurotransmitters are referred to when two or more of them are present in the same nerve terminal.
- a protein that causes the final pinching-off of the membrane that completes the production of coated vesicles in the synaptic vesicle cycle.
- recycling process for synaptic vesicle. Process takes about 1 minute.
- Vesicles that contain small molecule neurotransmitters. These vesicles appear clear in electron micrographs. Made in the axon terminal by enzymes shipped down by slow axonal transport from the soma.
- an ATPase involved in priming synaptic vesicle for fusion
5 True/False Questions
large dense-core vesicles → Package neuropeptides. These vesicles are much larger in size than small clear-core vesicles. Made in the soma and shipped down to the terminal via fast axonal transport.
acetylcholine (ACh) → A neurotransmitter found primarily at neuromuscular junctions of the striated muscles and in the visceral motor system. Involved in muscle contraction and heart rate increases.
Electrical synapses → reversibly binds to synaptic vesicles and may cross link vesicle to actin filaments in the cytoskeleton to keep the vesicles tethered within the reserve pool.
end plates → neuromuscular junctions when synapses from the pre-synaptic axon elaborate and appear in a saucer-like shape on the muscle fiber
end plate potential (EPP) → make up EPPS and correspond to the release of just one or two vesicle. Small, happen spontaneously, and cannot trigger an AP.