Language of Medicine Chapter 16- Pathology

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Chabner's Language of Medicine, 9th edition. Pathology for Chapter 16- Skin/Integumentary system

basal cell carcinoma

malignant tumor of the basal cell layer of the epidermis

squamous cell carcinoma

malignant tumor of the squamous epithelial cells in the epidermis

malignant melanoma

Cancerous growth composed of melanocytes; due to intense exposure to sunlight

callus

increased growth of cells in the keratin layer of the epidermis caused by pressure or friction

keloid

hypertrophied, thickened scar developing after trauma or surgical incision

keratosis

thickened and rough lesion of the epidermis; associated with aging or skin damage

alopecia

absence of hair from areas where it normally grows

ecchymosis, ecchymoses

Bluish-purplish mark (bruise) on the skin.

petechia, petechiae

small, pinpoint hemorrhage

pruritus

itching

urticaria (hives)

acute allergic reaction in which red, round wheals develop on the skin

acne

chronic papular and pustular eruption of the skin with increased production of sebum

burn

Injury to tissues caused by heat contact.

cellulitis

diffuse, acute infection of the skin marked by local heat, redness, pain, and swelling

eczema

inflammatory skin disease with erythematous, papulovesicular lesions

gangrene

death of tissue associated with decreased blood supply

impetigo

Bacterial inflammatory skin disease characterized by vesicles, pustules, and crusted-over lesions.

psoriasis

chronic, recurrent dermatosis marked by itchy, scaly, red plaques covered by silvery gray scales

scabies

contagious, parasitic infection of the skin with intense pruritus

vitiligo

loss of pigment (depigmentation) in areas of the skin (milk-white patches)

lesion

An area of abnormal tissue anywhere on or in the body; may be caused by disease or trauma.

crust

Collection of dried serum & cellular debris;scab; a common skin lesion

cyst

thick-walled, closed sac or pouch containing fluid or semisolid material; a common skin lesion

erosion

wearing away or loss of the epidermis; a common skin lesion

fissure

Groove or crack-like sore; a common skin lesion

macule

flat lesion measuring less than 1 cm in diameter; a common skin lesion

nodule

solid, round or oval elevated lesion more than 1 cm in diameter; a common skin lesion

papule

Small (less than 1 cm in diameter), solid elevation of the skin (pimples); a common skin lesion

polyp

growth extending from the surface of mucous membrane; a common skin lesion

pustule

papule containing pus; a common skin lesion

ulcer

open sore on skin or mucous membranes (deeper than an erosion); a common skin lesion

vesicle

small collection (papule) of clear fluid (serum); blister; a common skin lesion

wheal

smooth, edematous (swollen) papule or plaque that is redder or paler than the surrounding skin; a common skin lesion

first-degree burns

superficial epidermal lesions, erythema, hyperesthesia, and no blisters

second-degree burns (partial-thickness burn injury)

epidermal and dermal lesions, erythema, blisters, and hyperesthesia

third-degree burns (full-thickness burn injury)

Epidermal and dermis are destroyed (necrosis of skin), and subcutaneous layer is damaged, leaving charred, white tissue.

exanthematous viral diseases

Rash (exanthem) of the skin due to a viral infection; ex) rubella (German measles), rubeola (measles), and varicella (chickenpox)

scleroderma

chronic progressive disease of the skin and internal organs with hardening and shrinking of connective tissue

systemic lupus erythematosus (SLE)

chronic autoimmune inflammatory disease of collagen in skin, joints, and internal organs

tinea

infection of the skin caused by a fungus

leukoplakia

white, thickened patches on mucous membrane tissue of the tongue or cheek

nevus, nevi

pigmented lesion of the skin

verruca

epidermal growth (wart) caused by a virus

Kaposi sarcoma

malignant, vascular, neoplastic growth characterized by cutaneous nodules

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