| Term | Definition |
|---|
| Somatic Nervous System | sends sensory info from body to the CNS; sends motor info from the CNS to skeletal muscle. |
| Autonomic Nervous System | Regulates heart rate, blood pressure, respiration, pupil dilation and constriction, digestion and glandular secretion. |
| Sympathetic Nervous System (Part of ANS) | Arouses and prepares fight or flight, mydraiasis dilation of the pupils. |
| Parasympathetic Nervous System(Part of ANS) | Rejuvenates and relaxes the body; miosis constriction of the pupils |
| Neurotransmitters | Message carriers released in response to nerve action potential, interact with specific receptor sites that are found in the postsynaptic fiber and the effector organ, action is determined by the neurotransmitter substance. |
| Neurotransmitter in PANS | Called Acetycholine formed between pre and post ganglionic nerves of pans and sans also termed cholinergic. |
| Neurotransmitter in SANS | Noprepinephrine; released from postganglionic nerves; termed adrenergic |
| Four Drug Groups | Cholinergic (P+), Anticolinergic (P-), Adrenergic (S+) Andrenergic Blocking Agents (S-) |
| Direct Acting Agents of P+ | Include the choline derivativea acetlycholine and pilocarpine, long duration and very selective compared to PANS stimulants. Uses include urinary retention, glaucoma and xerostomia. |
| Indirect Acting Agents of P+ | Act on a receptor or causes the release of neurotransmitters, also known as choliesterase inhibitor, and is used for reversable agents include some drug overdoes and myathenia gravis (muscles paralyzed for no reason). |
| Anticholinergic Agents (P-) | Prevent action of acetlycholine at the postganglionic PANS endings. The release of acetylcholine is not prevented, but anticholinergic agents block the receptor site. |
| Major Neurotransmitter of SANS | Epinephrine, Norepinephrine, Dopamine, Isoproterenol |
| Direct Action of S+ | Produces effects directly on the receptor by stimulating the receptor. |
| Indriect Action of S+ | Leads to the release of endogenous norepinephrine, which then produces a response. |
| Mixed Action of S+ | Can either stimulate the receptor directly or release endogenous norepinephrine to cause a response. |
| Alpha receptors | Stimulation results in smooth muscle excitation or contraction which causes vasoconstriction. |
| Beta 1 receptors | Excitation causes stimulation of heart muscles |
| Beta 2 receptors | Stimulation produces bronchodialation in the lungs |
| Mechanism of action of S+ | Epinephrine has alpha and beta receptor activity, Norepinephrine has primarily alpha receptor activity, Isoproternol has primarily beta receptor activity. |
| Beta Blockers | More activity on the heart and blood vessels, less activity on the lungs, fewer side effects, lower chances of causing drug interactions. REMEMBER BETA BLOCKERS END IN "OLOL" |
Combine with other sets
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