Exam 2: Anti-microbial drugzzzz

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Penicillins, cephalosporins, vancomycin (also imipenem and aztreonam)

Inhibition of cross-linking (transpeptidation) of peptidoglycan via beta-lactam ring

Cycloserine, bacitracin

Inhibition of other steps in peptidoglycan synthesis

Chloramphenicol, erythromycin, clindamycin

Action on 50S ribosomal subunit

Tetracyclines (and aminoglycosides)

Action on 30S ribosomal subunit

Sulfonamides (and trimethoprim)

Inhibition of nucleotide synthesis via competitive inhibition as PABA agonist.

Quinolones

Inhibition of DNA synthesis via inhibiting DNA gyrase.

Rifampin

Inhibition of mRNA synthesis

Amphotericin B (nystatin, ketoconazole)

Antifungal activity

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