| Term | Definition |
|---|
| Gram + PG | 5 AA Interbridge between Lys and Ala |
| Gram - PG | No interbridge - direct link between DAP and Ala |
| Teichoic Acids | Gram + only. Carbohydrate that through PG, may help w/movement of ions, PG attach to cell memb. |
| Periplasm G+ | No defined space for - loses periplasm more quickly |
| Periplasm G- | Located in periplasmic space - retains periplasm longer |
| Periplasm | gel substance secreted by CM containing metabolic enzymes |
| G- CW | Periplasmic space-PG layer-Periplasmic space, OM |
| Outer Membrane | hydrophobic asymmetric lipid biayer: CM/PPS/PG/PPS/(Proximal Leaf/Distal Leaf) |
| Proximal leaf | phospholipid |
| Distal leaf | Lipopolysaccharide (LPS) |
| LPS | Lipid A, Core (polysaccharide), O-specific side chains |
| Porins | hydrophillic material channels through OM |
| Lipoproteins | anchor OM to PG |
| LPS and LTA | Toxic components of G- and G+ |
| LTA | Teichoic Acids complexed w/lipids |
| Peptidoglycan | Tetrapeptide chains and NAG-NAM sugar backbone |
| Transpeptidase | links Tetrapeptide chains via interbridge (G+) or direct link (G-) |
| Beta-lactam antibiotics | Penicillin (and others) bind to transpeptidase, leading to PG loss |
| Vancomycin | Blocks NAM-NAG synthesis. Too big for G-, so G+ only |
| Acid Fast CW | CM/PG/Mycoloic Acid gives hydrophobic structure |
| Isoniazid (INH) | Disrupts mycolic acids (AFB) |
| Mycoplasma | no cell wall! |
Combine with other sets
Share on Facebook
Share on MySpace