Pharm Unit 2 Drugs

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mark_suguitan  on October 25, 2011

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Pharm Unit 2 Drugs

Benzocaine
Ester Local Anesthetic
1/67
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Benzocaine Ester Local Anesthetic
Cocaine Ester Local Anesthetic
Tetracaine Ester Local Anesthetic
Procaine Ester Local Anesthetic
Bupivacaine Amide Local Anesthetic
Lidocaine Amide Local Anesthetic
Ropivacaine Amide Local Anesthetic
Nitrous Oxide Inhaled General anesthetic
Halothane Inhaled General anesthetic
Isoflurane Inhaled General anesthetic
Desflurane Inhaled General anesthetic
Sevoflurane Inhaled General anesthetic
Sodium Thiopental (Pentothal) Barbiturate IV General Anesthetic
Thiamylal (Surital) Barbiturate IV General Anesthetic
Methohexital (Brevital) Barbiturate IV general Anesthetic
Diazepam (Valium) Benzodiazepine (long-half life)
-IV general Anesthetic
-status epilepticus
-cerebral palsy and other spastic states
Lorazepam (Ativan) Benzodiazepine (short acting)
-IV general Anesthetic
-Status epilepticus
-Do not undergo hepatic microsomal oxidation conjugated directly
Midazolam (Versed) Benzodiazepine
-IV general Anesthetic
Morphine Opioid
- IV general Anesthetic
Fentanyl Opioid
-IV general anesthetic
Propofol (Dlprivan) IV general anesthetic
Etomidate (Amidate) IV General Anesthetic
Ketamine (ketalar) IV General Anesthetic
Heroin Opioid
Oxycodone Opioid
Meperidine Opioid
Codeine Opioid
Propoxyphene Opioid - Partial agonist
Nalbuphine Opioid
Butorphanol Opioid
Pentazocine Opioid
Tramadol Opioid
Buprenorphine Opioid - Partial agonist
Naloxone/ Naltrexone Opioid Antagonist
Methylnaltrexone Opioid
Diphenoxylate Opioid
Loperamide Opioid
Dextromethorphan Opioid
Nalfurafine Opioid
Chloral Hydrate Alcohol
-Sedative and hypnotic
Buspirone Partial 5HT agonist / D2 angonist-antagonist
-anxiolytic effects only - generalized anxiety
-no cross tolerance with BZ and no potentiation of other S/H drugs
-not going to develop dependence - therefore use with past Hx of substance abuse
Oxazepam Benzodiazepine (short acting)
-does not undergo hepatic microsomal oxidation
Zolpidem, zaleplon, eszopiclone Interact at the BZ receptor site (GABAa) - antagonist by Flumazenil
-management of sleep disorders w/o daytime sleepiness
Flumazenil Benzodiazepine receptor antagonist
Ramelteon Melatonin receptor agonist
-rapid onset of sleep but no maintenance.
SE: increase serum prolactin and decrease serum testosterone
Phenobarbital Barbiturate (short acting)
-Selective anticonvulsant at high doses w/o severe sedation
clonazepam Benzodiazepine
-Selective anticonvulsant at high doses w/o severe sedation
-panic and phobic disorders
Meprobamate Carbamate
-Selective muscle relaxant
Triazolam Benzodiazepine (short acting)
-primary insomnia
Alprazolam (xanax) Benzodiazepine
-panic and phobic disorders
Flurazepam Benzodiazepine (long acting)
-primary insomnia
Imipramine Tricyclic Antidepressant
MOA: inhibits NE and 5-HT uptake
Chlorimipramine Tricyclic Antidepressant
MOA: inhibits 5HT uptake
Desipramine Tricyclic Antidepressant
MOA: inhibits NE uptake
Fluoxetine (prozac) SSRI
Citalopram (celexa) SSRI
Paroxetine (paxil) SSRI
Sertraline (zoloft) SSRI
Venlafaxine (effexor) SNRI
Duloxetine (cymbalta) SNRI
Phenelzine (Nardil) MAOI - irreversible for MAO-A & B
Beware of hypertensive crisis with tyramine containing foods
Selegiline MAOI- irreversible for MAO-B
Less likely to have hypertensive crisis
Moclobemide MAOI - reversible for MAO-A
Less likely to have hypertensive crisis
Lithium Mood stabilizer
USE: treatment of mania as monotherapy or with valproate of carbamazepine.
SE: low therapeutic index LOT OF SE!!! (monitor serum concentrations)
Valproate Anticonvulsant
Use: seizure
Also used as a Mood stabilizer - not protective against suicide
Lamotrigine Anticonvulsant
also used as a mood stabilizer
carbamazepine Anticonvulsant
also used as a mood stabilizer- not protective against suicide

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