Cellular Reproduction:Mitosis and Meiosis

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Created by:

JessikaZabala  on October 26, 2011

Subjects:

Biology 101

Description:

Lecture 5

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Cellular Reproduction:Mitosis and Meiosis

Functions of cell division
-Transmit heredity information
-gametes for sexual reproduction and daughter cells for asexual reproduction
-Replace old or worn out somatic cells
-Organism growth
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Functions of cell division -Transmit heredity information
-gametes for sexual reproduction and daughter cells for asexual reproduction
-Replace old or worn out somatic cells
-Organism growth
Chromosomes -DNA is packages into chromosomes
-chromosomes are compacted DNA bound with histones
-Number of chromosomes varies by species and somatic cells vs. gametes
-Humans have 46 chromosomes in somatic cells (23 from each parent)
Homologous chromosomes 1 from each parent
contains corresponding genes in the same location
-1-22 are autosomes and the 23rd pair is the sex chromosomes
Allele gene from parent
Locus location of gene
Centromere holds daughter chromatids together
attachment site during cell division
Telomeres are protective caps of repeating base pairs
Chromosome duplication -single chromatid replicates
-replicated chromosomes are held together by centromere
-sister chromatids will be separated into daughter cells
Cell Cycle -Interphase=G1, DNA synthesis, G2
-Cell division is mitosis or meiosis
Interphase Nucleus in tact
DNA not organized
cells are in interphase most of the time
G1 phase cell growth
cell differentiation depending on type of cell
S phase DNA synthesis
chromosomes replicated
G2 phase preparation for division
protein synthesis
Mitosis:Prophase Duplicated chromosomes condense
Spindle microtubules form
Spindle poles form centrosomes (organelles of spindle attachment)
Mitosis:Late Prophase -Nuclear envelope breaks down
-Centrosomes migrate to spindle poles
-Chromosomes become attached to spindle microtubules at their kinetochore
Mitosis:Metaphase -Longest stage of mitosis
-Chromosomes line up at poles
-Kinetochore of each sister chromatid are attached to microtubules from opposite poles
Mitosis:Anaphase shortest stage
chromatids separate
microtubules that are not attached to chromosomes lengthen -cell elongates
cell now contains two sets of independent and identical chromosomes
Mitosis:Telephase -Nuclear envelope reforms
-Chromosomes become less condensed and defined
-Cytokinesis occurs and cell is "pinched" in two
-Both daughter cells now in interphase
Mitosis in plants vesicles forms new cell wall at center from golgi
Binary fission asexual reproduction in protists
-includes mitosis
-all chromosomes are passed form parent to offspring
reproduction in prokaryotes
-does not include mitosis
-plasmid replicates and cell splits in two
sexual reproduction Parents pass on half of their chromosomes to offspring
increased genetic variation through
-gene recombination
-crossing over
Meiosis: Cell division for sexual reproduction diploid parent cells are divided into haploid daughter cells
during meiosis number of chromosomes is reduced
ex. 2 chromosomes separate into two cells and then split into 4 cells
Meiosis 1: Prophase 1 Duplicated chromosomes condense
homologous chromosomes pair up and chiasmata occur as chromatids of homologous exchange parts by crossing over
the nuclear envelope disintegrates and spindle microtubules form
Meiosis 1: Metaphase 1 Paired homologous chromosomes line up along the equator of the cell
one homologue of each pair faces each pole of the cell and attaches to the spindle microtubules via the kinetochore
Meiosis 1: Anaphase 1 Homologues separate
One member of each pair goes to each pole
Sister chromatids do not separate
Meiosis 1: Telophase 1 Spindle microtubules disappear
2 clusters of chromosomes have formed each containing one member of each pair of homologues
the daughter nuclei are haploid
cytokinesis occurs
little or no interphase between meiosis 1 and 2
Meiosis 2: Prophase 2 Recondense chromosomes
Spindle microtubules re-form and attach to the sister chromatids
Meiosis 2: Metaphase 2 chromosomes line up along the equator with sister chromatids of each chromosome attached to kinetochore microtubules that lead to opposite poles
-independent assortment happens here
Meiosis 2: Anaphase 2 chromatids separate into independent daughter chromosomes
one former chromatid moving toward each pole
Meiosis 2: Telophase 2 chromosomes finish moving to opposite poles
nuclear envelopes reform
chromosomes decondense again
Four haploid cells Cytokinesis results in 4 haploid cells each containing one member of each pair of homologous chromosomes
Independent assortment chromosomes shuffled in random ways in daughter cells
Crossing Over duplicated lined up homologous chromosomes
stick together (chiasma)
parts exchange

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