Odontogenic Tumor

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Created by:

kramvm01  on October 27, 2011

Subjects:

Oral Pathology

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Odontogenic Tumor

Odontogenic Tumor
Derived from the epithelial and or mesenchymal remnant of the tooth forming appatatus
-thus only in maxilla and mandible
-unkown cause
-asymptomatic
-mimic microscopically the cell or tissue of origin
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Terms

Definitions

Odontogenic Tumor Derived from the epithelial and or mesenchymal remnant of the tooth forming appatatus
-thus only in maxilla and mandible
-unkown cause
-asymptomatic
-mimic microscopically the cell or tissue of origin
Epithelial Tumor Ameloblastoma SEEN MOST COMMONLY
Originates within the mand. and max from epithelium that is involvedin formation of teeth
Enamel organ
Odontogenic rest(rests of Malassez, rest of Serres)
Reduced enamel epithelium
Epithelial lining of odontogenic cysts (esp. dentigerous cysts)
Rest of Malassez most commomly seen
Ameloblastoma Stimulus for neopastic trasformation=unkown
Seen in Adults
-40yrs
-anywhere in mand. or max
-Mand. molar=ramus area most favored
-asymptomatic / seen as jaw expansion
Ameloblastoma -cause tooth movement and malocclusion
Osteolytic, typically found in tooth bearing area of jaws
unilocular or multilocular
margins well defined and sclerotic -slow growing
Know* MER= multilocular expansile radiolucency
Ameloblastoma Peripheral (extraosseous) amelobastoma
-on gingiva
-older adults (40-60yrs)
CysticAmeloblastoma
-may perforate bone
-recurrence rate=40%
Younger age = 35 yrs
Ameloblastoma Malignant Ameloblastoma
-difficult to control locally
-Metastases may appear usually in lungs
-Also to regional lymph nodes
Treatment
No single standard type
-Individualize
Curettage (50% recurrence) go in a cm on either side/bone graft
Block resection (larger lesions)
Ameloblastoma Cont Not a high recurrance rate
Cystic ameloblastoma and peripherial may be treated less aggressively.
-Asymptomatic red or white plaque or as ulcerated and malignant lesions should be treated as carcinomas
Follow patients indefinitely
-Radiotherapy not generally used.
Calcifying Epithelial Odontogenic Tumor 2nd most common
CEOT
-Pindborg tumor
-origin of cells throught to be dental lamina reminants ans stratum intermedium of enamel organ.
40yrs old
mand. twice as maxilla affected
molar ramus areas
-islands if calcification
-islands of epithelium
tumor-solid
Calcifying cont. Jaw expansion are seen on x-rays
associated with impacted teeth
Unilocular or multilocular (honeycomb)
Maybe completely radiolucent or may be opaque foci (amyliod) may be all white, all black, or salt and pepper.
Well circumscribed
Test Question:ball of calcification
Calcifying cont. concentric calcific deposits (Liesegang rings)seen in the amyloid material(look like bulls eye target)
Treatment = enucleation to resection
-slow growing
-some invasive potential
-metastases have not been reported
-recurrence rate =20%
Test question: (Liesegong rings) balls of calcification
Radiolucent as you get older radiopaque
Adenomatoid Odontogentic Tumor3rd most common
-duct like or gland like structure , but is odontogenic tumor
more like hamatoma than neoplasm of salivary gand
-ages 5-30yrs (2nd decade) teenages
-Females most
-anterior maxilla
-associated with crowns of impacted teeth.
radiolucency
Well circumscribed white border unilocular lesion
-usually around the crown of impacted tooth
-usually radiolucent but may have opaque foci
-may see divergence of roots
Treatment= conservative enucleation
all most never come back
Mesenchymal tumors Odontogenic Myxoma Mimics microscopically dental pulp or follicular connective tissue.
Benign neoplasm
-may be infiltrative and aggressive
may recur
mean age=30yrs
no gender
anywhere in maxilla or mand.
radiolucency
Odontogenic Myoma cont.radiolucency, quite variable
Well circumscribed or diffuse lesion
often multlocular
cortical expansion or perforation
DD= ameloblastoma or central hemangioma
Treatment= surgical excision
Moderate recurrence because loose, genlatinous consistency and absence of encapsulation
But prognosis is good (does not metastaize
Central Odontogenic Fibroma 2nd most common fibroma
-rare
-central counterpart too peripheral odontogenic
fibroma
maxilla and mand.
all age groups
radiolucent lesionlesions (multlocular)
Treatment:surgical enucleation
Cementoblastoma-3rd most common fibroma
-mesincimal cells
"true cementoma"
rare, benign neoplasm of cementobast
Ages= 2nd and 3rd decades ( before 25 yrs.)
No gender
Mand, most (posterior) molars
intimately associated with root of tooth- obliterates the root
may cause cortical expansion
-Low grade intermittent pain
Opaque lesion that replaces the root of the tooth
usually surrounded by radiolucent ring
Treatment: it cannot be removed without sacrificing tooth
Recurrence not seen
Periapical Cementoosseous Dysplasia "Cementoma" formerly known as
A reactive or dysplastic process (not a neoplastic one)
-not a tumor
Relatively common
at apex of vital teeth
no biopsy
black females
40 yrs means age
anterior mad. painless
black, black or white, all white, 2 or 3 teethusually
No Biopsy in or root canal ( vital tooth) this is on final
Periapical Cemnetoosseous Dysplasia cont Anterior mand. teeth (22-27)
Often two or more apices of teeth
found on routine x-rarys
first sign is periapical lucency
as matures, the lucent lesion develops into a mixed pattern of lucency/opacity
final stage isa solid, opaque mass surrounded by a thin lucent ring
just watch
Periapical Cementoosseous Dysplasia cont Florid, cemento-osseous dysplasia (florid means Flowery or excessive)
exuberant for periapical cemental dysplasia
blackfemales (25-60 yrs)
Typically bilateral all 4 quads.
Treatment =none, teeth are vital
Mixed (Epithelial and Mesencymal) Tumors Mixed
Amelobastic fibroma
Amelobastic fibro-odontoma
-both are benign mixed odontogenic tumor composed of neoplastic epithelium and mesenchyme
See in younge people
age 12 yrs
Mand. molar ramus are most common are affected
no gender
impacted tooth of you ng kid 12 yrs.
Ameloblastic Fibroma and Ameloblastic Fibro-Odontoma Maybe associated with impacted tooth
Well circmscribed with sc;erotic border
unilocular or multilocular
Opaque focus in ameloblastic fibro-odontoma is due to an odontoma
Treatment: Conservative curettage or excision
OdontomaMixed odontogenic tumor
Epithelial and mesenchymal dental hard tissue (enamel and dentin)
Compound odontoma =numerous miniature teeth (anterior jaw) max. and mand. small teeth cluster of 5 to 10 teeth
Complex odontoma =amorphous congiomerations of hard tiisue posterior mush not seeth
Most common odontogenic tumor
children and young adults
second decade of life
maxilla>mad.
usually see retained deciduous tooth and impacted tooth alveolar swelling
No symptoms
Compound odontoma= numerous tiny teeth in single focus
Complex odontoma=amorphous opaque mass ( in tooth bearing area
Treatment =enucleation ( no recurrence)

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