Gram Positive Bacilli of Medical Importance

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GP Bacilli

Only bacteria that form endospores.

Clostridium

This GP bacilli genus is a produces endospores under anaerobic conditions.

pulmonary

This type of anthrax has a 50/50 survival rate

capsules, endospores, exotoxin

3 virulence factors of B. anthracis. (CEE)

C. perfringens

GP Bacillus; causes myonecrosis (gas gangrene).

Clostridium botulinum

The most powerful microbial toxin known.

L. monocytogenes

GP bacillus, not self-limiting because it's intracellular. 20% death rate.

Flagella, avoids humoral immune system, resistant to all extremes

3 virulence factors of Listeria monocytogenes.

Listeria monocytogenes

GP bacillus, doesn't form endospores, associated mostly with deli meats.

Erysipelothrix rhusiopathiae RHUS

GP bacillus that causes Erysopeloid.

GP, acid fast

How are Mycobacterium bacilli characterized?

Corynebacterium diphtheriae

Filamentous psudomembrane of the pharynx forms first. Causes toxemia, inflammation of heart muscle, nerve endings.

droplets, fomites, contaminated milk

Three ways that Croynebacterium diphtheriae can be transmitted.

attachment & growth factors

Two virulence factors of Corynebacterium diphtheria are __________ and ______ factors

Erysipelothrix rhusiopathiae

GP bacillus that is zoonotic, cutaneous only and causes swollen, dark red lesions that burn and itch.

Propionibacterium

Genus of the GP bacillus that causes acne.

Mantoux skin test

Tuberculosis is tested by the _______ skin test.

Primary

Type of tuberculosis that causes immediate infection.

Secondary

Tuberculosis with gradual increase of symptoms caused by dormant cells.

Extra-pulmonary

Tuberculosis that's escaped the lungs and has the highest fatality rate.

fine droplets of mucus inhaled

Tuberculosis is spread from person to person how?

aerobe

Mycobacterium is a GP/GN bacillus that is acid-fast and is a strict _______.

saprobes

Many mycobacterium are ________.

Mycobacterium tuberculosis

GP bacillus that forms a "fortress" around itself with complex cords and waxes.

hijacked swollen macrophages

What is the outer protective layer of Mycobacterium tuberculosis made of?

Mycobacterium leprae

GP bacillus; strict parasite, slowest growing, treatment depends on type you have.

tuberculoid

Type of mycobacterium leprae that presents with shallow skin lesions and is easily treated.

leprotamous

type of leprosy that causes disfiguration due to bacteria growing in macrophages in cooler body regions.

borderline

type of leprosy that results in loss of feet or hands (neurologic complications)

Actinomycetes israeli

GP filamentous bacillus that has a role in dental caries.

Actinomycosis

Genus of GP filamentous bacillus that resides in the oral cavity, tonsils or intestine and can infect cervico-facial, thoracic or abdominal region.

Nocardia brasiliensis

GP filamentous bacillus that causes symptoms similar to TB.

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