Lipids II

Created by SidSzyd 

Upgrade to
remove ads

Carnauba Wax

Hardest and most useful wax. Found in brasilian tree

Lanolin Wax

From sheep wool.

Survanta and curosurf (phospolipids) is used to treat ?

respiratory distress syndrom (RDS)

phosphatidylcholine

phospo lipid only on cytosol side. goes to outside during apoptosis.

filipase

enzyme envolved with phosphatidylcholine

phosphatidyl inositol

used in cell signaling and metabolism. PIP in periphery of cell.

Ceramide

sphingosine + fatty acid
found in animal membranes
holds skin together
functions in apoptosis

sphingomyelin

has ceramide. lower concentrations than phospatidylcholine. Most abundant ceramide.

Ether glycerophospholipids

ether linkage at C1 of glycerol. PFA and plasmalogen. found in white matter.

ethanolamine plasmalogen

found in nervous system. not in plants, fungi or bacteria.

Glycolipids = ?

cerebrosides, globoside, ganglioside

cerebroside = ?

- 1 sugar + ceramide

Galactocerebroside

- type of cerebrosdie
only found in neural tissue

Glucocerebroside

type of cerebroside
found in other tissues besides neural

globoside

has 2 sugars instead of 1

ganglioside

oligosaccharide attached instead of monosaccharide. used in cell to cell signaling.

cardiolipids

only found in mitochondria and bacteria
test for syphilis

sulfolipids

brain lipids. sulfate esters of cerebrosides.

sphingolipidoses

Lipid storage disease. passed on through x chromosomes. Most die 3-5 yo.

Tay-Sachs Disease

GM2 accumulation in brain.
Hexodsminidase deficiency

Fabry's disease

ceramide trihexoside in kidney
Alpha galactosidase deficiency

Krabbe's disease

galactocerebroside in white matter
globoid leukodystrophy
galactocerebrosidase deficiency

Gaucher's disease

glucocerebroside in the spleen and liver
lysosomal glucocerebrosidase deficiency
most common
erosion of bones

Imiglucerase (Cerezyme)

analogue of human β-glucocerebrosidase used to treat Gaucher's disease

Miglustat (Zavesca)

a glucosylceramide synthase inhibitor. prevents build up of fatty acids in Gaucher's disease.

Metachromatic leukodystrophy

accumulation of sulfogalactocerebroside in CNS
arylsulfatase A deficiency

metachromasia

nerves stain yellowish-brown with cresyl violet dye in metachromatic leukodystrophy

Generalized gangliosidosis

accumulation of ganglioside GM1
deficiency of GM1 ganglioside: b-galactosidase

Niemann-Pick disease

sphingomyelin accumulation in reticuloendothelial.
sphingomyelinase deficiency

Niemann-Pick Type A and B (I)

Missing acid sphingomyelinase (ASM)

Niemann-Pick Type C

body cannot properly break down cholesterol and other fats

Niemann-Pick Type D

problems with the movement of cholesterol between brain cells.

A antigens
B antigens
H antigens

Type A blood
Type B blood
Type O blood

Ganglioside Nomenclature
1
2
3

1. Gal-GalNAc...
2. GalNAc...
3. Gal-Glc...

Please allow access to your computer’s microphone to use Voice Recording.

Having trouble? Click here for help.

We can’t access your microphone!

Click the icon above to update your browser permissions above and try again

Example:

Reload the page to try again!

Reload

Press Cmd-0 to reset your zoom

Press Ctrl-0 to reset your zoom

It looks like your browser might be zoomed in or out. Your browser needs to be zoomed to a normal size to record audio.

Please upgrade Flash or install Chrome
to use Voice Recording.

For more help, see our troubleshooting page.

Your microphone is muted

For help fixing this issue, see this FAQ.

Star this term

You can study starred terms together

NEW! Voice Recording

Create Set