Hepatic Disease in Cats
About this set
Created by:
lunazzurra on November 6, 2011
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Description:
Dr. Marcella Ridgway
University of Illinois
VM610
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19 terms
Terms | Definitions |
|---|---|
 What are 3 common features in feline liver disease clinical signs? | - Hepatomegaly - Hypersalivation - Jaundice |
| What are 3 major differences in the way cats handle bilirubin (compared to dogs)? | - Cats are deficient in glucoronyl transferase - They rapidly become deficient in protein carriers and BR ligands if they aren't taking in protein - They require taurine to conjugate their BA's |
| What are the top 3 reasons for jaundice in cats? | - Hepatic lipidosis - Cholangitis - Lymphosarcoma |
| Why is bilirubinuria in a cat ALWAYS a cause for concern? | - it's never normal: no renal conjugation of bilirubin as in dogs - cats have higher renal threshold (i.e., if you're seeing BR in the urine, there's a LOT of it in the system) |
| Why is elevated ALP in a cat ALWAYS a cause for concern? | - ALP has very short half-life in cats - no corticosteroid induced ALP as in dogs (cALP) |
| Name 5 aspects of hepatic disease that are unique to cats, aside from bilirubinuria. | - Increased ALP always cause for concern - GGT very sensitive indicator of liver disease & can be very high - Hypoalbuminemia UNcommon - Ascites UNcommon - Prognosis better than in dogs |
| What serum biochemistry finding in hepatic lipidosis in cats is an exception to the typical changes they undergo with liver disease? | - Normal GGT |
| Name 3 extrahepatic conditions in cats associated with increased ALT. | - hyperthyroidism - intestinal disease/IBD - pancreatitis |
| True or false: a coagulation profile is less important in a cat with suspected liver disease than in a dog with suspected liver disease. | False. The opposite is true. |
| What pattern of chemistry values might guide you toward a diagnosis of cholangitis rather than lipidosis? | An ALT that is dramatically elevated and much MORE elevated than either GGT or ALP. |
| Which form of cholangitis in cats is associated with triaditis? | Neutrophilic |
| Compare and contrast neutrophilic and lymphocytic cholangitis in cats in terms of signalment, areas affected, and signs | Neutrophilic: older cats, involves bile ducts, cats very sick Lymphocytic: younger cats, does NOT involve bile ducts, cats less sick |
| Which form of cholangitis in cats is associated more commonly with ascites? | Lymphocytic |
| How is lymphocytic cholangitis in cats treated? | Immunosuppressive drugs |
| What form of fat accumulates in the livers of cats with hepatic lipidosis? | Triglycerides |
| Which form of hepatic lipidosis in cats is more common, primary or secondary? | Secondary |
| Name 4 risk factors for hepatic lipidosis in cats. | - obesity - rapid weight loss - stress - anorexia |
| Describe the liver enzyme values in a cat with hepatic lipidosis. | - NORMAL GGT - Dramatically elevated ALP - ALT slightly increased |
| What are the 2 most important nutrients to give cats with hepatic lipidosis? | - Arginine - Carnitine |
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