chromosomal theory of inheritance
Mendelian genes have specific positions on chromosomes, and it is the chromosomes that undergo segregation and independent assortment.
the production of offspring with combinations of traits differing from those found in either parent
process in which homologous chromosomes exchange portions of their chromatids during prophase I of meiosis
A genetic map based on the frequencies of recombination between markers during crossing over of homologous chromosomes
A unit of measurement of the distance between genes. One map unit is equivalent to a 1% recombination frequency.
Duchenne muscular dystophy
Progressive weakening of the muscles and loss of coordination - caused by a lack of muscle protein called dystophin. Inheritance pattern: X-linked recessive
sex-linked recessive disorder defined by the absence of one or more proteins required for blood clotting
A sex-linked recessive trait in which an individual cannot perceive certain colors
a kind of mutation in which the order of the genes in a section of a chromosome is reversed
change to a chromosome in which a fragment of one chromosome attaches to another nonhomologous chromosome
A human genetic disease resulting from having an extra chromosome 21, characterized by mental retardation and heart and respiratory defects
XXY - males that are characterized by small testes and long legs and enlarged breasts and reduced sperm production
cri du chat
a chromosomal deletion in chromosome 5 that results in children who are mentally retarded, have small heads, and have a cry that sounds like a loud cat; they die at a young age
A genetic abnormality in which a child cannot metabolize phenylalanine, an amino acid, which consequently builds up in the body and causes mental retardation
Tay Sach's Disease
human genetic disease caused by a recessive allele for a dysfunctional enzyme, leading to accomidation of a certain lipid in the brain. Most common in Ashkenazic Jews.
genetic disorder caused by a recessive allele for a chloride channel protein; characterized by an excessive secretion of mucus and consquent vulnerability to infection
caused by a dominant allele. genetic disorder that causes progressive deterioration of brain cells. symptoms do not appear until the age of 30 or so