Bronchodilators

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ipratropium bromide

Atrovent

Tiotropium bromide

Spiriva

atropine

Dey Dose

ipratropium bromide and albuterol

Combivent,Duondeb

biolterol

Tornalate

metraproterenol

Metrapel Alupent

terbutaline

Brethren Brethare Bricanyl

albuterol

Proventil Ventolin

pirbuterol

Maxair

salmaterol

Serevent

levalbuterol

Xopenex

isoetharine

Bronkosol

isoproterenol

Isuprel

Atrovent

ipratroprium bromide

Spiriva

tiotropium bromide

Combivent,Duondeb

ipratroprium and albuterol

Dey Dose

atropine

Tornalate

biolterol

Metrapel Alupent

Metraproternol

Brethine Brethare Bricanyl

terbutaline

Proventil Ventolin

albuterol

Maxair

pirbuterol

Serevent

salmaterol

Xopenex

levalbuterol

Xanthines

theophylline theobromine aminophylline caffeine

racemic epinepherine

Micronephrin Vaponephrin

Pro drug

Class of extended release drugs

Tertiary

Increased effect with every dose

Quarternary

Docent distribute through body when inhaled

Rescorinol

Won't break down when taken orally

Saligenins

Longest lasting B agonists

Theobromine

Found in cocoa,caffeine

Theophylline

Found in tea leaves

Less than 5 mcg / ml

No effect on bronchodilation but still have side effects

Less than 20 mcg / ml

Nausea

30 mcg / ml

Cardiac arythmias abnormal rhythm

40 mcg ml

Seizures

Peptic ulcer,acute gastritis

Do not give theophylline of pt has

Side effects theophylline

Gastric disturbance,headache,dizziness,hypotension

Pro drug

What classbis administered in an inactive form and must be converted in body to active form(sustained release)

Levalbuterol

R isomer is potent in

Atropine

Causes dry mouth because it stops mucous production when it goes to CNS

Phosphodiesterase

Enzyme that breaks down cAMP

Downregulation

After long term use there is an increase in B2 receptors called

Tachyphylaxis

Decrease in response to a drug occurring shortly after admin

12

Mt drugs can last .....hours

Rescorinols

Class of drug that has rapid onset, and can be taken orally so is resistant to COMT

Xanthines

Class that Indirectly bronchiodilate by inhibiting cAMP

Beta 2

Diapause vascular smooth muscle in lungs,skeletal,uterus,blood vessels,coronary cerebral

isoetharine biolterol

Greater B2 than B1

Isoproterenol

B1 and B2 equally

norepinepherine and dopamine

Mostly A but some B1 and B2

A,B1,B2 equally

racemic epinephrine,MicroNephrin,Vaponephrin

Status amasticus

An asthmatic that dosent respond to normal meds

Carbon positions

Difference in catecolamine and catecholamine derivative is based on attachment site to

levalbuterol Xopenex

Is pure R isomer of Racemic albuterol

terbutaline and albuterol

Greatest B2 selectivity band minimal cardiac side effects

Orally taken

Rescorinols

Nebulizer stregnths

0.31 mg,0.63 mg,1.25 mg

S

Isomer considered to be inactive on adrenergic receptors

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