HUTM
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15 terms
Terms | Definitions |
|---|---|
 found in the space of Disse | autonomic nerve fibres and type III collagen fibres (reticulin fibres) |
| kuppfer cells | resident macrophages of the liver |
| stellate cells | regulate sinusoidal diameter, store vitamin A and synthesize reticulin fibres |
| the basis of the liver acinus | blood flow (zones) |
| epithelium of the gall bladder | single layer of tall columnar cells with apical microvilli. contains numerous mitochondria |
| gall stone composition | cholesterol, bile pigments and proteins |
| components of the portal tract | hepatic artery, portal vein, bile ducts, lymphatics, nerves (all ensheathed in CT) |
| Glisson's capsule | collagenous capsule covering the external surface of the liver |
| functions of zone 1 | protein synthesis and activities that require oxidative phosphorylation |
| functions of zone 3 | metabolism of drugs and toxins (cytochrome P450 system) |
| characteristics of zone 1 | small, more mitochondria, more rER |
| characteristics of zone 3 | larger, fewer mitochondria, more sER, more alcohol dehydrogenase |
| relationship between gall stones and cholecystitis | over 90% of chronic cholecystitis cases are associated with gall stones |
| mechanism of chronic cholecystitis | gall stones obstruct the outflow of bile, raising luminal pressure and allowing bile salts to penetrate into the wall. |
| the location of most cell death in chronic venous congestion in relation to the liver lobule | zone 3: slowing of blood reduces supply to this area |
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