Goljan Environmental Path - Mech Injury

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Created by:

SnickerC  on November 15, 2011

Subjects:

Pathology

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Goljan Environmental Path - Mech Injury

Types of skin wounds (3)
Contusion (bruise)
Abrasion
Laceration
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Definitions

Types of skin wounds (3) Contusion (bruise)
Abrasion
Laceration
Contusion (bruise) Blunt force injury to blood vessels with subsequent escape of blood into tissue
Abrasion Superficial excoriation of the epidermis
Laceration Jagged tear with intact bridging blood vessels, nerves, and connective tissue
Incision Wound with sharp margins with severed bridging blood vessels
Gunshot wounds (2) (1) Contact wounds
(2) Stellate-shaped
Gunshot wounds Contain soot and gunpowder (fouling)
Contact gunshot wound: fouling
Gunshot wounds
Intermediate-range wounds
Powder tattooing (stippling) of the skin around the entrance site
Gunshot wounds
Long-range wounds
No powder tattooing
Exit wounds Typically larger and more irregular than entrance wounds
Motor vehicle collisions most common cause of accidental death in people ages 1 to 39 years
Motor vehicle collisions Frequently cause mechanical injury
Frequently alcohol-related
Shaken baby syndrome More than 50% of deaths in child abuse are due to this syndrome.
Shaken baby syndrome (age) Majority are <1 year old
Characteristic signs of shaken baby syndrome (3) (1) Retinal hemorrhages
(2) Multiple fractures of long bones
(3) Subdural hematomas
First-degree burns (2) (1) Painful partial-thickness burns (e.g., sunburn)
(2) Heal without scarring
Second-degree burns (4) (1) Painful partial-thickness burns
(2) Damage to entire epidermis
(3) Blister formation
(4) Usually heal without scarring
First- and second-degree burns: no permanent scarring
Third-degree burns (4) (1) Painless full-thickness burns
(2) Extensive necrosis of epidermis and adnexa
(3) Scarring is inevitable.
(4) Healing of epithelial surface
Scarin in third-degree burns (a) Keloids (exaggerated scars) commonly occur.
(b) Potential for developing squamous cell carcinoma
Healing of epithelial surface in third-degree burns Proliferation of residual epithelium located at burn margins and lining adnexal structures
Complications of burns (2) (1) Infection

(2) Curling's ulcers (stomach)
Most common cause of death in burn patients sepsis caused by Pseudomonas aeruginosa
Minor heat syndromes (3) Heat edema
Heat cramps
Heat exhaustion
Heat edema
(1) Mild ______ of feet, ankles, and hands
(2) Cutaneous ___________ with pooling of blood in gravity-dependent extremities
(3) Occurs in the _________nonacclimatized individuals; healthy travelers coming from __________ environment
(4) Self-_________
swelling

vasodilation

elderly/cold to hot

limited
Heat exhaustion: ≤ 40°C (<104°F); no anhidrosis/no mental status changes
Heat exhaustion
(1) Significant ____________ (salt and water depletion) with or without increase in body temperature
(a) Orthostatic __________, dizziness, headache, nausea/vomiting
(b) Core temperature ________; normal to 40°C (104°F)
(c) No __________ (absence of sweating); normal mental status examination
volume depletion

hypotension

variable

anhidrosis
Heat exhaustion
Laboratory studies
(a) ________________________
(b) Variable serum ___ depending on previous intake
______________ (no intake), normal, or _____________ (patient drank water without electrolytes)
Hemoconcentration (e.g., ↑ hemoglobin/hematocrit)

Na+

Hypernatremia

hyponatremia
Heat exhaustion
Treatment
Intravenous volume and electrolyte replacement
Heat exhaustion may progress to heat stroke if not treated promptly
Major heat syndrome: heat stroke
Major heat syndrome
Similar presentation as heat exhaustion, except the following
(1) Core body temperature > 40°C (104°F)
(2) Anhidrosis; mental status (e.g., do not know time, date) and CNS dysfunction (e.g., ataxia, cerebral edema, seizures)
Major heat syndrome treatment (1) High-flow O2; intravenous fluids (normal saline, Ringer's lactate)
(2) Rapid cooling to < 40°C (104°F)
Heat stroke > 40° C (>104° F), anhidrosis (absence of sweating), impaired consciousness
Frostbite Pathogenesis (1) Localized tissue injury caused by direct damage (e.g., ice crystallization in cells)
(2) Indirect damage (e.g., vasodilation, thrombosis)
Frosbite
Clinical findings

(1) Loss of __________ or burning/tingling sensation
(2) ________ of the skin; waxy appearance; cold to the touch
(3) Left untreated, skin gradually ____________________ and blisters
pain sensation

Discoloration

darkens (becomes completely black)
Frostbite treatment principles
(1) Pre-thaw:_______________________________
(2) Thaw: immerse in circulating water 37°C to 40°C; ibuprofen
(3) Post-thaw __________________________
stabilize core body temperature; rehydration



dry and elevate body part
Electrical injury Produced by alternating current (AC) and direct current (DC)
__ is more dangerous than __.

AC/DC
AC

DC
AC produces tetanic contractions.
DC produces a single shock.
Wet skin decreases _______, which increases ________. resistance

current
Dry skin increases resistance, which decreases _______. current
Tissue damage increases with increased voltage and duration of exposure.
Current moving from the left arm to the right leg

(1) Most dangerous route, because ___________
(2) Death results from _________________.
it affects the heart

cardiorespiratory arrest
Lightning injury
_________ deaths/year
Hair on end; buzzing
Mortality rate ___ with direct strike
100 to 200

30%
Drowning
Common cause of death in
children from 1 to 14 years of age
Drowning refers to death by suffocation from immersion in liquid.
Near drowning is defined as survival following asphyxia secondary to submersion
Diving reflex occurs in water that is colder than 20°C (70°F).
Diving reflex
(1) __________
(2) Peripheral _________
Shunts blood to more vital areas.
(3) Blood shifting
Shift to thoracic cavity to prevent ________
(4) Allows both conscious and unconscious person to _________________
Bradycardia

vasoconstriction

lung collapse

survive longer without O2
Most common drowning wet drowning
∼90% of cases
wet drowning
Initial laryngospasm on contact with water followed by
relaxation and aspiration of water
Dry drowning is characterized by intense laryngospasm without aspiration
Lung aspiration of fresh water (90% of cases)
(1) Due to its hypotonicity, water is reabsorbed from the alveoli into the _____________
(2) Plasma is diluted causing ___________________ (hemoglobinuria), hyponatremia, hyperkalemia.
(3) Electrolyte abnormalities precipitate ______________.
Most common cause of death
(4) Hemoglobinuria can produce ________________.
pulmonary circulation.

hemolysis of RBCs

ventricular fibrillation

acute renal failure
Lung aspiration of salt water (10% of cases)
(1) Salt water is more isotonic to blood (no ___________).
(2) Cause of death is _________________
RBC hemolysis

asphyxia from pulmonary edema.
High altitude: O2 concentration 21%, ↓ atmospheric pressure
High altitude
Decreased
barometric pressure
Hypoxemic stimulus to chemoreceptors increases the respiratory rate producing respiratory alkalosis.
Decrease in Paco2 causes a corresponding increase in Pao2
Respiratory alkalosis activates ________

Increased synthesis of _____________________
glycolysis

2,3-bisphosphoglycerate
High altitude: respiratory alkalosis; right-shifted OBC
Right-shifts O2-binding curve (OBC) increases release of O2 to tissue
Acute mountain sickness usually occurs at above 8000 feet (2440 m) elevation
Risk factors of acute mountain sickness (2) Increased rate of ascent
Extreme altitude
Clinical findings of acute mountain sickness: (1) Headache (most common)
(2) Fatigue, dizziness, anorexia, insomnia
(3) Acute pulmonary edema
Noncardiogenic (exudate)
(4) Acute cerebral edema
Ataxia, stupor, coma
Acute mountain sickness treatment Immediate descent (if severe complications)

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