Physical and psychological dependence on and craving for a drug
Drug action in which the combination of two similar drugs is equal to the sum of the effects of each
particles of drug suspended in air
exaggerated hypersensitivity reation to a previously encountered drug or foreign protein
combination of two drugs gives less than a additive effect (action)
agent given to counteract an unwanted effect of a drug
commercial name for a drug: trademark or trade name
chemical formula for a drug
factors that prevent the use of a drug or treatment
drugs that produce tolerance and dependence and have potential for abuse or addiction
prolonged use of a drug that may lead to physiologic need for its actions in the body
amount of drug administered, usually measured in milligrams
Food and Drug administration (FDA)
U.S. government agency having the legal responsibility for enforcing proper drug manafacture and clinical use
legal noncommercial name for a drug
condition caused by treatment (drugs or procedures) given by physicicans or medical personnel
unexpected effect produced in a particularly sensitive patient but not seen in most people
adminstration of drugs in gaseous or vapor form through the nose or mouth
study of new drug synthesis; relationship between chemical structure and biological effects
study of interaction of drugs and their target molecules such as enzymes, or cell surface receptors
drugs are given by mouth
drugs are given by injection into the skin, muscles, or veins (any route other than throughthe digestive tract). Examples are subcutaneous, intradermal, intramuscular, intravenous, intrathecal, and intracavitary injections
specialist in preparing and dispensing drugs
location for preparing and dispensing drugs; also the study of preparing and dispensing drugs
study of the effects and strength of a drug within the body
study of drug concentration in tissues and body fluids over a period of time
specialist in the study of the properties, uses, and actions of drugs
study of the preparation, properties, uses, and actions of drugs
Physicians' Desk Reference (PDR)
reference book that lists drug products
target substance with which a drug interacts in the body
drugs are inserted through the anus into the rectum
lack of beneficial response: seen when drugs are unable to control the disease process
desired and benifical effect of a drug
exact timing and frequency of drug administration
adverse reaction, usually minor, that routinely results from the use of a drug
drugs are given by placement under the tongue
combination of two drugs causes an effect that is greater than the sum of the individual effects of each drug alone. Also known as potentiation.
instrument (tube) for introducing or withdrawing fluids from the body
larger and larger drug doses must be given to achieve the desired effect. the patient becomes resistant to the action of a drug as treatment progresses
drugs are applied locally on the skin or mucous membranes of the body; ointments, creams, and lotions are applied topically
harmful effects of a drug
study of harmful chemicals and the effects on the body
movement of a drug across a cell membrane into body cells
United States Pharmacopeia (USP)
authoritative list of drugs, formulas, and preparations that sets a standard for drug manufacturing and dispensing
substance found in foods and essential in small quantities for growth and good health
lowers blood pressure. Angiotensin-converting enzyme (ACE) inhibitors block the conversation of angiotensin I to angiotensin II (a powerful vasconstrictor)
central nervous system stimulant used to prevent narcolepsy (seizures of sleep), to suppress appetite and to calm hyperkinetic children.
Reduces or eliminates sensation; general and local.
angiotensin II receptor blocker (ARBs)
lowers blood pressure by preventing angiotensin from acting on receptors in blood vessels
neutralizes acid in the stomach
slows the uptake of androgens or interferes with their effect in tissues
treats abnormal heart rhythms
Chemical substance, produced by a plant or microorganism, that has the ability to inhibit or destroy foreign organisms in the body. Examples are antifungals, cephalosporins, erythromycin, tetracycline, antituberculars, penicillins, quinolones, and sulfonamides.
prevents blood clotting
prevents convulsions (abnormal brain activity)
relieves symptoms of depression
drug given to prevent or treat diabetes mellitus
Prevents nausea and vomiting
blocks the effects of histamine and helps prevent symptoms of allergy
relieves nausea and vomiting; antiemetic
reduces the tendency of platelets to stick together and form a clot
inhibits the secretion of acid by cells lining the stomach
acts against viruses such as herpesviruses and HIV
reduces estrogen in the blood by blocking the enzyme aromatase
inhibits bacterial growth
blocks the action of epinephrine at sites on receptors of heart muscle cells, the muscle lining of blood vessels, and bronchial tubes; antiarrhythmic, antianginal, and antihypertensive
prevents bone loss in osteoporosis and osteopenia
central nervous system stimulant that is used in drugs to relieve certain types of headache by constricting cerebral blood vessels.
calcium channel blocker
blocks the entrance of calcium into heart muscle and muscle lining of blood vessels; used as an antiarrhythmic, antianginal, and antihypertensive; also called calcium antagonist
increases the force of contraction of the heart
Drugs that act on the heart and blood vessels. This category of drug includes ACE inhibitors, beta-blockers, calcium channel blockers, cholesterol-lowering drugs or statins and diuretics
lowers cholesterol by preventing its production by the liver; statin
increases the production of urine and thus reduces the volume of fluid in the body; antihypertensive
female hormone that promotes development of secondary sex characteristics and supports reproductive tissues
Relieves symptoms of diseases in gastrointestinal tract. Ex: antacids, antiulcer drugs, antidiarrheals, cathartics, laxatives, purgatives, and antinauseants (antiemetics).
hormone from the adrenal cortex that raises blood sugar and reduces inflammation
produces sleep or a trance-like state
habit-forming drug (potent analgesic) that relieves pain by producing stupor or insensibility (also known as opioids); morphine and opium are examples.
female hormone that stimulates the uterine lining during pregnancy and is also used in treatment of abnormal uterine bleeding and for hormone replacement therapy
relieves constipation; strong cathartic
Treats asthma, emphysema, and infections that affect breathing; bronchodilators are examples
a mildly hypnotic drug that relaxes without necessarily producing sleep. Benzodiazepines are examples.
excites and promotes activity. caffeine and amphetamines are examples
stimulates cellular metabolism
controls anxiety and severe disturbances of behavior; also called anxiolytics.
A type of parenteral administration in which an injection is made into a body cavity such as the peritoneal or pleural cavity,
A procedure in which drugs are introduced into the plerual cavity of people who have pleural effusions due to malignant disease. The drug causes the pleural surfaces to adhere.
A type of parenteral adminitstration in which a shallow injection is made into the upper layers of the skin.
Subcutaneous (hypodermic) injection (SC)
A type of parenteral administration in which a small hypodermic needle is introduced into the subcutaneous tissue under the skin, usually on the upper arm, thigh, or abdomen.
Intramuscular injection (IM)
A type of parenteral administration in which an injection of the muscle is given usually in the buttock or upper arm.
A type of parenteral drug administration in which instillation occurs in the space under the membranes (meninges) surrounding the spinal cord and brain. Also known as a Lumbar puncture.
Intravenous injection (IV)
A type of parenteral drug administration in which the injection is given directly into a vein.
Battery-powered ___, may be used for continuous administration of drugs by the subcutaneous or intravenous route.
A type of topical application that is used to deliver drugs continuously through the skin; such as estrogen for hormone replacement therapy, pain medication, and nicotine for smoking cesation programs.
A unexpected effect that occurs in the patient after administration of a drug.
nonsteroidal anti-inflammatory drugs (NSAIDS)
Act on tissues to inhibit prostaglandins (hormone-like substances that sensitize peripheral pain receptors). Reduces fever, pain, and inflammation.
An agent that reduces or eliminates sensation in all tissues of the body.
An agent that reduces or eliminates sensation in a particular region.
An anticoagulant that blocks the formation of a number of clot-forming factors in blood. Reversed by Vitamin K.
Tissue-type plasminogen activator (tPA)
An anticoagulant that dissolves clots and is used to open vessels after myocardial infarction.
A natural anticoagulant purified from pig intestine or bovine(cow) lung.
tricyclic antidepressants (TCAs)
Antidepressants that increase the action of neurotransimtters by blocking their removal (reuptake) from the synapses (spaces between nerve cells). (1)
selective serotonin reuptake inhibitors (SSRIs)
An antidepressant that increases the action of neurotransimtters by blocking their removal (reuptake) from the synapses (spaces between nerve cells). (2)
monoamine oxidase inhibitors (MAOIs)
Antidepressants which increase the length of time neurotransmitters work by blocking monoamine oxidase, an enzyme that normally inactivates neurotransmitters.
Drugs used to treat symptoms of Alzheimer disease. They act by aiding brain neurotransmitters (acetylcholine) or sheilding brain cells from glutamate, a neurotransmitter that at high levels contributes to death of brain cells.
an antidiabetic used to treat type-1 diabetes
An oral antidiabetic drug that lowers the levels of glucose in the blood by stimulating the production of insulin. Treats Type-2 diabetes.
Oral antidiabetic drugs that increase the body's sensitivity to insulin and reduces the production of glucose by the liver. Treats Type-2 diabetes.
An oral antidiabetic drug that temporarily blocks enzymes that digest sugars. Treats Type-2 diabetes.
An oral antidiabetic drug that enhances glucose uptake into tissues. Treats Type-2 diabetes.
An oral antidiabetic drug that stimulates the beta cells in the pancreas to produce insulin. Treats Type-2 diabetes.
A cardiovascular drug perscribed to dilate coronary blood vessels before other drugs are used.
A cardiovascular drug that helps the heart pump more forcefully in heart failure.
A cardiovascular drug binds to dietary cholesterol and prevents its uptake from the gastrointestinal tract.
Selective estrogen receptor modulator (SERM)
An endocrine drug has estrogen-like effects on bone and on lipid metabolism. Used to treat post-menopausal osteoporosis and breast cancer.
An endocrine drug and thyroid hormone that increases calcium in the blood and promotes bone deposition.
Growth hormone release-inhibiting factor (somatostatin)
An endocrine drug that can be manufactured. It inhibits production of natural growth hormone.
ranitidine (Zantac) and cimetidine (Tagamet)
Gastrointestinal drugs and histamine H2 receptor antagonists that turn off histamine, which promotes secretionof stomach acid.
A gastrointestinal drug that works by stopping acid production by proton pump inhibition.
Anti-TNF (tumor necrosis factor) drugs
Gastrointestinal drugs that are used to treat autoimmune diseases, such as Crohn's. Also used against rheumatoid arthritis.
A respiratory drug that opens bronchial tubes and is administered by injection or aerosol inhaler.
A respiratory drug that is inhaled or given intravenously and orally to reduce chronic inflammation in respiratory passageways.
A respiratory drug that prevent asthma attacks by blocking leukotriene (a bronchocostrictor) from binding to receptors in respiratory tissues.
Barbiturates and Benzodiazepines
Two major categories of sedative-hyponotics that depress the central nervous system and promote drowsiness and sleep.
A minor tranquilizer that controls minor symptoms of anxiety.
A major tranquilizer that is used to control more severe disturbances of behavior.
The most complete and up-to-date listing of drugs that gives information about their characteristics and clinical usage as approved by that particular hospital.
Drugs that treat osteoporosis and are designed to increase bone formation, prevent bone loss and increase calcium deposition.
A newer class of NSAIDS that block the effects of a specific part of the pathway that produces prostaglandins. Increase the risk of clots and heart attacks but have fewer GI side effects than tradition NSAIDS.
Treats fungal infections that occur in the skin, vagina, mouth, bloodstream, and other organs.
Treats tuberculosis, a chronic and often drug-resistant infection.
A severe allergic reaction that could include dyspnea, hypotensin, and, loss of consciousness.