NAME: ________________________

Macroglides, tetracyclines, aminoglcosides and fluroquinolones pharm test #2 Test

Question Types


Start With


Question Limit

of 33 available terms

Upgrade to
remove ads

5 Written Questions

5 Matching Questions

  1. levaquin
  2. avelox
  3. lincosamides
  4. common macrolide agents
  5. cipro
  1. a -broad spectrum of action; lower respitory infections, UTIs, bone, skin
  2. b -sub cat of macrolide
    -bacteriostatic/cidal
    -clindamycin: activate against most gram + and anaerobic org., absorbed better than lincocin vis gi tract, maintains a higher serum drug conc and fewer toxic effects
    -lincomycin
    -s/e: gi upset, rash
    -adverse rxn: colitis, anaphylactic shock
    -drug interactions: aminophyline, dilantin, barbiturates, ampicillin
  3. c -primarly treats URIs, acute sinusitis, chronic bronchitis, UTIs.
    -may cause dysrhythmias
  4. d -erthromycin (iv)
    -clarithromycin
    -azithromycin (long 1/2 life) (iv)
    -dirithromycin
  5. e -more active against s. pneumoniae than levaquin is

5 Multiple Choice Questions

  1. -readily absorbed from the GI tract; excretion in bile, feces, urine
    -only a small amy is excreted in urine, therefore renal insufficiency is not a contraindication for macrolide use
  2. -inhibits bacterial protein synthesis
    -gram - bact
    -reserved for serious infections
    -not absorbedvia GI tract; does not cross BBB
    -IM/IV only
    -gentamycin, tobramycin, amikacin, streptomycin
    -s/e: ototoxicity, nephrotoxicity, superinfection
    -peak levels drawn to monitor toxicity
    -troug levels to monitor maintenance of therapeutic drug levee
  3. -bacteriostatic
    -oral prepL onset of action 1 h, peak conc is 4 hrs and duration is 6hrs
  4. -vanocomycin
    -s/e: nephrotoxicity, ototoxicity damage (8th cranial nerve) can be permanent or temp, chills, dizziness, fever, rash, n/v
  5. may increase serum levels of:
    -theophyline
    -carbamazepine
    -warfarin
    -do not administer with antacids bc may increase peak levels of macrolide

5 True/False Questions

  1. common examples of Fluoroquinolones-cipro
    -levaquin
    -avelox

          

  2. pharmacodynamics of aminoglycosides-IM/IV
    -shot half life; given 3-4 days daily
    -excreted via urine

          

  3. intermediate acting Tetracyclines-PO only
    -Sumycin

          

  4. side effects/adverse run of macrolide-gi n/v/d/ abdominal cramping
    -allergic rn are rare
    -when combined with other hepatotoxic drugs leads to hepatotoxicity; usually reversible when the drug is discnt.

          

  5. pharmacokinetics of ketolides-orally: absorption by GI tract
    -not affected by food intake
    -excreted through feces, urine
    -t-1/2: 10 hrs

          

Create Set