Ch. 14 DNA and Gene: Synthesis and Repair
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16 terms
Terms | Definitions |
|---|---|
double helix | double stranded molecule |
complementary base pairing | A&T, C&G |
genome | entire complement of DNA |
DNA Polymerase | polymerizes deoxyribionucleotides to DNA |
origin of replication | the replication bubble forms at a specific sequence of bases |
replication fork | y-shaped region where the parent-DNA double helix is split into two single strands |
leading strand, or continuous strand | leads into the replication fork and is synthesized continuously |
lagging strand, or discontinuous strand | lags behind the synthesis occurring in the fork |
Okazaki fragments | short sections about 1000 base pairs long |
DNA ligase | formation of a phosphodiester bond between fragments |
replisome | all the enzymes required for DNA synthesis organized into a machine |
telomere | the region at the end of a chromosome |
telomerase | catalyzes the synthesis of DNA from an RNA template. Acts as a built in template allowing telomerase to add DNA onto the end of a chromosomes and prevent it from getting shorter |
proofread | DNA polymerase- if the wrong base is added during DNA synthesis, the enzyme pauses, removes the mismatched base that was just added, and then proceeds with synthesis |
mismatch repair | occurs when mismatched bases are corrected after the DNA synthesis is complete |
necleotide extension repair | process of removing a damaged region in in one strand of DNA and correctly replacing it using the undamaged strand as a template |
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