Infectious Diseases of the Nervous System (104)
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Created by:
stevenypark Plus on November 24, 2011
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20 terms
Terms | Definitions |
|---|---|
 List 3 organisms that cause meningitis in neonates up to 2 months. | Strep. agalactiae E. coli Listeria monocytogenes |
| List 3 organisms that cause meningitis in infancy and childhood. | Strep. pneumoniae N. meningitidis H. influenzae |
| List an organism that causes meningitis in adolescents. | N. meningitidis |
| Name 4 organisms that cause meningitis in people between the ages of 20 and 60. | Strep. pneumoniae N. meningitidis L. monocytogenes gram-negative bacilli |
| Does bacterial or viral meningitis cause a greater inflammatory response? |  bacterial menigitis - gyral patterns obscured - patchy strokes in the brain cause ischemic injuries and subsequent swelling |
| What happens to blood vessels involved in bacterial meningitis? |  vasculitis |
| List 3 causes of fungal meningitis. | Cryptococcus Candida Aspergillus Mucor - restricted to immunocompromised |
| What type of hydrocephalus is associated with tuberculous meningitis? |  communicating hydrocephalus - granuloma pictured |
| What type of meningitis is associated with endarteritis obliterans? | tuberculous meningitis - thickening of vessel wall and compression of lumen --> can lead to infarcts |
| What is the most common cause of viral encephalitis worldwide? | HIV |
| List 3 viruses that are noteworthy causes of aggressive encephalitis in immuncompromised hosts. |  HSV CMV VZV - microglial nest pictured |
| List 3/5 neuropathies associated with HIV-1. | encephalitis leukoencephalopathy vacuolar myelopathy neuropathy inflammatory myopathy |
| List some opportunistic infections associated with HIV-1. | CMV VZV Candida Papova virus (PML) <-- white matter Mycobacteria |
| What type of cancer is associated with HIV-1? | CNS lymphoma |
| What virus that causes encephalitis can induce the formation of giant cells? |  HIV - giant cell encephalitis |
| Describe the inclusion bodies associated with CMV. |  intranuclear basophilic inculsion bodies |
| Which cells are affected by progressive multifocal leukoencephalopathy? |  oligodendrocytes |
| What type of stain can be used to diagnose primary CNS lymphoma? |  reticulin |
| Creutzfeldt-Jakob Disease s/s (2) |  rapidly progressive dementia - loss of neurons - vacuoles packed with prions myoclonus |
| List 2 ways in which variant CJD differs from sporadic CJD. |  slower onset more personality changes - can be diagnosed by immunohistochemistry |
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