+ve ss RNA enveloped viruses
Order by
23 terms
Terms | Definitions |
|---|---|
 retroviruses | virus family, all integrate and mutate but dont cause acute disease, acc contain reverse transcriptase |
| retroviruses | virus family, replication→latency, persistence, chronic disease, eg tumours, immunosuppression, ICD |
| FeLV | most important immunosup disease in UK cats |
| FeLV | cats, viruses labile & cell assoc., transmission by close contact / leucocytes in blood/milk/semen, vaccines |
| FeLV | cats, viraemia notable in BM, thymus, salivary gland and repro tracts, 40% recover, 30% viraemice w/out Ab, 30% die/intermittent excretors |
| FeLV | cats, cause repro failure, immune disease, multicentered/thymic/alimentary lymphosarcomas |
| FeLV | cats, test for envelope protein, antigen or capsid protein by sandwich ELISA, immunochromatography gives no false +ves, virus isolation at Glasgow |
| Sheep Pulmonary Adenomatosis | sheep, mammalian type D virus causing alvolar lining cell proliferation, ++fluid (wheelbarrow test), slow growing tumours and death. cull infected. |
| Avian Leukosis Virus | birds, avian Type C, vert/horiz transfer, subgroup A&B in 10% layers → B cell leukosis, subgroup J in 40% broilers→myeloid tumours, death, vaccine |
| Bovine Leukosis Virus | →bovine LN tumours, notifiable, cleared in 1999 by MAFF |
| FIV | cats, lentivirus, receptor CD134, isolates of varying virulence, transmission via saliva, milk, grooming, biting, mating. 10% of wandering males, ELISA for Ab or "one-step", no vaccine, neuter, |
| CD134 | FIV receptor found on monocyte-derived macrophages & activated T cells |
| FIV | cats, virulent isolates→progressive CD4 (on Th cells) decline, high circulating virus→remission w/ ++Ab response (can→immune exhaustion)→rapidly progresses→feline AIDS or chronic immunosuppression |
| Visna Maedi Virus | sheep, rep in lung macrophages→brain, lungs, udder, joints, 2-6yrs→ICD Type IV, wasting (demyelination) and dyspnoea |
| Lentivirus | gennus characterised by long incubation periods, new variants arising every few months, causing immunosuppresssion and immune complex diseases |
| Visna Maedi Virus | sheep, infected animals remain virus&Ab+ve, transmission in aerosol, milk, colostrum, confirm w/ AGDT/ELISA, cull sero+ve, accreditation if 2 clear tests |
| Caprine Arthritis/Encephalitis Virus | goats lentivirus |
| Caprine Arthritis/Encephalitis Virus | goats, →ICD, encephalitis in kids, insidious polyarthritis in adults, in 10% British herds, 4% animals, clinical disease rare |
| Caprine Arthritis/Encephalitis Virus | goats, transmitted by mixing milk, sharing colostrum, so pretreat colostrum 56C for 1hr then artificial milk, keep kids/+ve mother separate |
| Equine Infectious Anaemia | aka Swamp Fever |
| Equine Infectious Anaemia | horses, lentivirus, notifiable |
| Equine Infectious Anaemia | infected horses have lifelong latent infection in macrophages, →Typpe III ICD, non-neutralising Ab + compliment →RBC lysis, death |
| Equine Infectious Anaemia | horses, carriers for several yrs despite Ab, transmission by swamp flies, needles, semen, milk, test spleen for Ab (immunodiffusion) or antigen (IF), slaughter, notifiable |
First Time Here?
Welcome to Quizlet, a fun, free place to study. Try these flashcards, find others to study, or make your own.