AP 13 Brain & Nerves Part 6 - Meninges

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Chapter 13 Brain and Nerves Part 6 - Meninges, Bentricles and Cerebrospinal Fluid

Meninges

connective tissue membranes; Dura mater: superficial, Arachnoid mater: middle, Pia mater: bound tightly to brain; Spaces: subdural, Subarachnoid

Dura Mater

(tough mother) superficial, tightly bound to internal periosteum exept: Falx, cerebri, Tentorium cerebelli, Falx cerebelli, Venous sinuses

Falx Cerebri

in longitudinal fissure between the two cerebral hamispheres

Tentorium Cerebelli

between cerebellum and cerebrum

Falx cerebelli

between 2 cerebellar hemispheres

Venous Sinuses

form at bases of 3 folds - all 3 at base of dura matter

Arachnoid Mater

Thin, wispy layer; looks like spider web; just inferior to dura mater

Pia Mater

thin, delicate CT membrane closely adhered to brain; follows external contours of brain and dips into every sulci and covers every inch of space

Subdral Space

between dura and arachnoid mater; only small amount of serous fluid within; keeps dura and arachnoid from sticking together

Subarachnoid Space

between arachnoid and pia mater; contains web-like strands of arachnoid, blood vessels, and cerebrospinal fluid; contains all nutrients that feed CNS

Blood Supply to Brain

brain requires tremendous amound of blood; receives 15-20% of blood pumped by heart; interruption can cause unconsciousness and irreversible brain damage; receives blood from arteries; Blood brain barrier

High Metebolic Rate w/Blood Supply

dependent upon constant supply of oxygen and glucose

Arteries to Brain

internal carotids and vertebral arteries

Vertebral Arteries to Brain

join to form the basilar artery; usually see anurism with blockage of basilar artery

Carotids to Brain

carotids plus basilar form the cerebral arterial circle (cicle of willis); provides rest of artories to brain

Arteries of Brain Pic

Blood Bain Barrier

3 things that regulate what goes to CNS: 1)endothelial cells (lining all capillaries) have tight junctions between them; 2)Astrocytes have foot processes that influence capillary permeability; 3)Basement membrane of endothelium

Lipid Soluble Sub and Blood Brain Barrier

pass through by diffusion: nicotine, ethanol, heroin

Water Soluble Sub and Blood Brain Barrier

move through mediated (active) transport: amino acids, glucose

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