Nutrition Chapter 12: Water and major minerals

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Created by:

laurackerr  on November 29, 2011

Subjects:

Nutrition

Classes:

Nutrition FINAL

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Nutrition Chapter 12: Water and major minerals

functions of water in body fluids
- carries nutrients and waste products through body
- maintains the structure of large molecules like proteins and glycogen
- participates in metabolic reactions
- aids in regulation of body temp (sweat)
- solvent for minerals, vitamins, AAs, glucose, other small molecules so that they can participate in metabolic activities
- acts as lubricant/cushion around joints, inside eyes, spinal cord, in pregnancy surrounding amniotic sac
- maintains blood pressure
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functions of water in body fluids- carries nutrients and waste products through body
- maintains the structure of large molecules like proteins and glycogen
- participates in metabolic reactions
- aids in regulation of body temp (sweat)
- solvent for minerals, vitamins, AAs, glucose, other small molecules so that they can participate in metabolic activities
- acts as lubricant/cushion around joints, inside eyes, spinal cord, in pregnancy surrounding amniotic sac
- maintains blood pressure
how much of the total body weight of an adult does water constitute 60%
other water body facts - 75% of lean tissue weight is water
- <25% adipose tissue weight is water
- proportion of water in body is smaller in females, obese, elderly
where are fluids found in the body? - intracellular fluid
- interstitial fluid (between cells)
- intravascular fluid
what part of the body maintains water balance? the hypothalamus in the brain. About 2.5 L fluid in per day and about 2.5 L of fluid out per day
what is thirst? a constant desire to drink
what is dehydration? a condition in which water output exceeds water input. Symptoms:
- thirst
- dry skin/ mucous membranes
- rapid heartbeat
- low BP
- weakness
- death
what is water intoxication? rare condition in which body water contents are too high. Symptoms:
- confusion
- convulsions
- death
Sources of water input - liquids
- foods
- water created by metabolism
sources of water output - Kidneys
- Skin
- lungs
- feces
Minerals, generic - inorganic elements
- maintain their chemical identity (cannot be destroyed by heat, acid, O2 or changed into anything else)
- overdoses can be toxic
- bioavailability varies
Why does bioavailability of minerals vary? certain substances bind with minerals and prevent their absorption. Phytates (legumes and grains) and oxalates (green leafy veggies)
what are the major minerals? present and needed by the body in larger amounts
- sodium
- chloride
- potassium
- calcium
- phosphorous
- magnesium
- sulfur
what are the trace minerals? present and needed by body in smaller amounts
- iron
- zinc
- copper
- manganese
- iodine
- selenium
- molybdenum
how are major minerals divided into groups? - based on function
- minerals involved with fluid balance (sodium, chloride, potassium)
- minerals involved in bone health (calcium, phosphorus, magnesium)
which atoms have no electrical charge? sodium and chlorine
what happens when a mineral salt (like sodium chloride) disolves into water? it dissociates into ions
what is an ion? positively and negatively charged particles (Na+, Ca-)
- positively charged ions= cations
- negatively charged ions= anions
what are salts that dissociate into ions? electrolytes
what is electrolyte balance? when human body electrolyte solutions have the same number of + and - particles. should happen. Death can be a consequence if this does not happen
important body electrolytes cations:
- sodium
- potassium
- calcium
- magnesium

anions:
- chloride
- bicarbonate
- phosphate
- sulfate
Sodium chief function - principal cation of extracellular fluids
- maintains fluid and electrolyte balance
- helps maintain acid base balance
- assists in nerve transmission/ muscle contraction (Na in should=Na out)
deficiency symptoms and toxicity symptoms for sodium Deficiency: muscle cramps, mental apathy, loss of appetite

Toxicity: acute hypertension, edema
related sodium facts - 1 gm salt= 400 mg sodium
- 5 gm salt= 1 tsp
- 1 tsp salt= 2000 mg
- most health authorities recommend less than 2400 mg sodium/day
- minimum needs= 500 mg/ day
- high Na intake leads to high Ca excretion
sodium and hypertension - sodium (salt) does not cause hypertension in healthy people
- sodium (salt) causes high BP in people with salt sensitivity
- calcium can decrease BP
chloride chief function - chief anion of extracellular fluid
- maintains fluid and electrolyte balance
- part of HCl found in stomach
foods chloride is found in table salt, soy sauce, processed foods, foods with visible salt, salt spices, condiments, luncheon meats
*same as sodium
chloride deficiency and toxicity symptoms deficiency: do not occur under normal circumstances

toxicity: vomiting
chloride related facts - element chlorine (Cl2) is poisonous gas
- when chlorine reacts with sodium or hydrogen, it forms the chloride ion (Cl-)
- excessive vomiting of gastric juices upsets acid-base balance and leads to metabolic alkalosis (commonly observed in bulimia)
Potassium chief function - principal intercellular cation (K+)
- maintains normal fluid and electrolyte balance
- assists in nerve transmission and muscle contraction
*almost same as sodium, except intercellular
foods, deficiency symptoms for potassium - most whole foods (ubiquitous)
- deficiency is most common electrolyte imbalance
- results from diabetic acidosis, dehydration, prolonged vomiting, diarrhea, drugs (diuretics, steroids, laxatives)
- Symptoms: muscle weakness, paralysis, confusion
potassium toxicity symptoms toxicity occurs from potassium salts or supplements. Symptoms:
- muscle weakness, vomiting, renal failure

If administered intravenously it can stop the heart (uthenation)
other potassium facts - some diuretics are potassium "wasting" diuretics and potassium supplements are required.
- diets low in potassium increase risk of hypertension and stroke
- diets high in potassium decrease risk of hypertension and stroke
- RDA= 2000 mg/ day
- Bananas: 1 cup=600 mg
Calcium location and functions - most abundant mineral in the body
- 99% of bodys calcium is found in bones and teeth where Ca functions in mineralization of bones and teeth and stores Ca
- 1% of bodys calcium is found in body fluids where Ca is involved in blood clotting, muscle contraction, nerve transmission, BP maintenance
foods Calcium is found in milk/ milk products, small fish with bones, tofu, broccoli, greens, legumes (requires Calcium-Binding protein for absorption)
deficiency and toxicity symptoms for calcium deficiency: stunted growth in children, bone loss in adults (related to osteoporosis)

Toxicity: constipation, increased risk of urinary stone formation and kidney disfunction
calcium in bones - hydroxyapatite: calcium crystals in a protein matrix in bone
- calcium in bones is constantly remodeled, change in bone shape during bone growth from Ca++ deposition/reabsorption
related calcium facts - normal Ca= 9-11 mg/ day
- calcium rigor= increase Ca, causes death
- calcium tetany= decrease calcium, causes death
- Vitamin D controls calcium
Calcium absorption - adults absorb about 30% of calcium ingested
- pregnant women absorb 50%
- growing children absorb 50-60%
- calcium in supplements is not well absorbed (500 mg calcium gluconate tablet= 45mg absorbed)
what is required for calcium absorption? calcium binding proteins
things that enhance calcium absorption - vitamin D
- sugars (lactose)
- stomach acid
- hormones that promote growth
things that inhibit calcium absorption - lack of stomach acid (tums?)
- vitamin D deficiency
- high phosphorus intake
- high fiber diet (phytates, oxalates)
parathyroid hormone and blood calcium concentration - causes Vit D activation
- this leads to increased blood calcium or at least maintains current
calcitonin on blood calcium concentration - suppresses activation of vitamin D
- lowers blood calcium levels
what does active Vitamin D cause to happen - increased absorption of Ca from intestine
- increased reabsorption of Ca from bone (Ca leaves bone/ goes into bloodstream)
- increased reabsorption of Ca from kidney (Ca returned to blood supply as blood leaves kidney)

*Inactivated Vit D causes opp to happen
about how many people does osteoporosis affect? more than 25 million in the US/ year, mostly women
diagnosing osteoporosis - develops earlier without warning and not diagnosed till years later
- usually becomes apparent when someones hip suddenly gives way
- more than 300,000 people in the US are hospitalized each year with hip fractures.
What is osteoporosis? - means porous bone
- It is the loss of calcium from trabecular bone (lacy inner structure of calcium crystals that supports bone structure and provides the body's storage depot of calcium)
- it is a decrease in bone density
Osteoporosis cause, cure, bones most affected - cause: not known at present
- cure: not possible at present time
- Bone most affected: spine and pelvis bones
- Average female loses 6 inches in height from age 50-80 due to compression of bones in the spine. 2-6 girls: 1 boy
osteoporosis and menopause females going through menopause (loss of estrogen secretion) is associated with onset osteoporosis. In males, slowing of testosterone secretion (in aging process) is associated with onset of osteoporisis
things to increase risk for osteoporosis - being caucasian and east asian
- smoking
- alcoholsim
- low BMI
- estrogen deficiency and testerstone deficiency
things that decrease risk for osteoporosis - being African American
- weight bearing activity throughout life
- regular consumption of low-fat dietary foods (not food supplements)
Phosphorus chief function and location in body - 2nd most abundant mineral in body
- bone mineralization, buffering system, acid/base balance
- found in bones, teeth, part of every cell (phospholipids), genetic material, ATP
phosphorus foods, deficiency symptoms, toxicity symptoms, related facts - From all animal tissue
- deficiency symptoms: rare (usually drug induced making phosphorus unavailable), results in weakness and bone pain
- toxicity symptoms: rare, decreased calcium
- related facts: phosphoric acid in dark, carbonated beverages inhibits calcium absorption
Magnesium chief function, foods Chief function: bone mineralization, muscle contraction, nerve transmission, maintenance of teeth, immune integrity

foods: nuts, legumes, whole grains, dark veggies, seafood, cocoa
magnesium deficiency symptoms rare
- weakness
- confusion
- muscle spasms
- hypertension
magnesium toxicity symptoms - rare
- results from supplement intake--> diarrhea
- alkalosis
- dehydration
magnesium and the heart- magnesium is critical to nerve transmission/ muscle contraction of heart muscle
- protects against hypertensions and heart disease
- people living in areas with hard water (high concentrations of magnesium and calcium) tend to have lowered rates of heart disease
- magnesium deficiency= artery and capillary walls constrict which results in a hypertensive effect
sulfur sources and location - part of proteins, stabilize their shape by forming disulfide bridges
- part of vitamins biotin and thiamin
- part of hormone insulin
sulfur foods protein foods
sulfur deficiency symptoms not known, only with severe protein deficiency
sulfur toxicity symptoms rare
sulfur related facts - rigid body proteins (skin, hair, nails) are made of more sulfur containing AAs
- curly hair contains more sulfur- containing AAs

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