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nonspecific: physical barriers, phagocytes Natural immunity specific: cell mediated (innate), antibody mediated (adaptive) acquired immunity antigen presentation, recognition, activation, effect Immune response B2 agonists (albuterol), anticholinergics (ipratropium) asthma quick relief corticosteroids, long acting b2 agonists, anticholinergics, mast cell stabilizers, leukotriene modifiers, phosphodiesterase inhibitors, antibody asthma long term control b2 agonists (albuterol), anticholinergics (ipratropium), PDE inhibitors (theophylline) asthma bronchodilation drugs corticosteroids (beclomethasone), mast cell stabilizers (cromolyn), leukotriene modifiers (montelukast), antibody (omalizumab) asthma anti-inflammation drugs reversible airway obstruction albuterol indication b2 agonist at bronchial smooth muscle albuterol MOA arformoterol, formoterol, salmeterol long acting b2 adrenergic receptor agonists beclomethasone, budesonide, ciclesonide, flunisolide, fluticasone, triamcinolone, prednisone, methylprednisolone asthma corticosteroids reversible airway obstruction (asthma) triamcinolone indication decreased mediator synthesis, release, and infiltration of inflammatory cells triamcinolone MOA ipratropium, tiotropium asthma anticholinergics omalizumab asthma antibody beclomethasone, budesonide, ciclesonide, flunisolide, fluticasone, triamcinolone asthma corticosteroids albuterol, levalbuterol, pirbuterol asthma beta 2 agonists (short acting) arformoterol, formoterol, salmeterol asthma beta 2 agonists (long acting) montelukast, zafirlukast, zileuton asthma leukotriene modifiers cromolyn asthma mast cell stabilizers roflumilast, theophylline asthma phophodiesterase inhibitors