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5 Written questions

5 Matching questions

  1. What irreversible reaction drives the synthesis of UDP-glucose?
  2. What enzyme catalyzes the transfer of glucose from UDP-glucose to a growing chain?
  3. What converts Glucose 6 phosphate into glucose in liver?
  4. What are the properties of the presumptive branch point?
  5. What are the properties of Glycogen synthase?
  1. a Glycogen synthase catalyzes transfer of glucose from UDP-glucose to a growing chain
  2. b Glucose 6 phosphatase converts Glucose 6 phosphate into glucose for export out of the liver and transport to other tissues
  3. c A glycosyl unit from UDP glucose is transferred to the hydroxyl group at the C4 of the terminal glucose residue forming a alpha 1,4 glycosidic bond. Requires a glycogen molecule that is a minimum of 4 residues to which a glycosyl will be added
  4. d Must be at least 4 residues away from other branches. Links are alpha 1,6 glycosidic bond
  5. e PPi+ H2O=> 2Pi

5 Multiple choice questions

  1. The 4th glucose residue from the branch glucose
  2. Increases the number of terminal glucose residues which are site of action for glycogen phosphorylase and synthase. Branching increases rate of glycogen synthesis and degradation
  3. Alpha 1,6 glucosiase hydrolyzes the alpha 1,6 glucosidic bond to release a free glucose molecule
  4. Phosphoglucomutase is a phospho enzyme and converts Glucose 1 phosphate to glucose 6 phosphate for further metabolism
  5. Glycogen phosphorylase, Transferase, alpha 1,6 glucosidase, phosphoglucomutase

5 True/False questions

  1. What is Uridine Diphosphate?Uridine diphosphate is a nucleotide composed of uracil, ribose and pyrophosphate

          

  2. What is the overall reaction of glycogen phosphorylase activity?Glycogen (n residues) + Pi=> glucose-1-phosphate + Glycogen (n-1 residues)

          

  3. How is UDP-glucose formed?UDP-glucose is synthesized from Uridine triphosphate and glucose-1-phosphate via the enzyme UDP-glucose pyrophosphorylase

          

  4. What does transferase do?When glucose residues are removed to the "limit dextran" which is the 4th glucose residue from the branch glucose

          

  5. What is the overall reaction of UDP glucose formation?Glucose-1-phosphate +UTP =>UDP-glucose + PPi

          

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