5 Written Questions
5 Matching Questions
- What are the properties of the presumptive branch point?
- What role does UDP-glucose play in Glycogen synthesis?
- Why is branching important in glycogen synthesis?
- What is phosphoglucomutase?
- What converts Glucose 6 phosphate into glucose in liver?
- a Must be at least 4 residues away from other branches. Links are alpha 1,6 glycosidic bond
- b Phosphoglucomutase is a phospho enzyme and converts Glucose 1 phosphate to glucose 6 phosphate for further metabolism
- c Increases the number of terminal glucose residues which are site of action for glycogen phosphorylase and synthase. Branching increases rate of glycogen synthesis and degradation
- d Glucose 6 phosphatase converts Glucose 6 phosphate into glucose for export out of the liver and transport to other tissues
- e Glycogen synthesis involves transfer of glucose from UDP-glucose to a growing chain
5 Multiple Choice Questions
- PPi+ H2O=> 2Pi
- Glucose-1-phosphate +UTP =>UDP-glucose + PPi
- Glycogen (n residues) + Pi=> glucose-1-phosphate + Glycogen (n-1 residues)
- Uridine diphosphate is a nucleotide composed of uracil, ribose and pyrophosphate
- Alpha 1,6 glucosiase hydrolyzes the alpha 1,6 glucosidic bond to release a free glucose molecule
5 True/False Questions
What enzymes are involved in Glycogen degradation? → A glycosyl unit from UDP glucose is transferred to the hydroxyl group at the C4 of the terminal glucose residue forming a alpha 1,4 glycosidic bond. Requires a glycogen molecule that is a minimum of 4 residues to which a glycosyl will be added
What is glycogenin? → A very large, branched polymer of glucose residues. Most of the glucose residues are linked by alpha 1,4 glycosidic bonds. branches about every 10th residue are linked by alpha 1,6 glycosidic bonds
What enzyme catalyzes the transfer of glucose from UDP-glucose to a growing chain? → Glycogen synthase catalyzes transfer of glucose from UDP-glucose to a growing chain
What is the limit dextran? → The 4th glucose residue from the branch glucose
What does transferase do? → Transferase transfers the 3 terminal glucose residues from outer branch to the center, main linear branch