11/29

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Created by:

hms056  on December 6, 2011

Subjects:

Cell Bio

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11/29

JAX/STAT
receptor with associated protein kinase partner pathway
1/11
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Definitions

JAX/STAT receptor with associated protein kinase partner pathway
nonreceptor tyrosine kinase performs phosphorylation in associated protein kinase pathway
adenylyl cyclase ; cAMP ; PKA Signal Relay example:
activation of --- upregulates --- which results in --- activation
glucose/glycogen ; CREB ; gene Targets of cAMP/PKA:
enzymes associated with --- balance ; --- mediated changes (acts as transcription factor) in --- expression
cytoplasmic PIP2 is found on the ---- face of the membrane
PIP2 phosphorylated form of phosphatidylinositol
PIP2 ; PLC ; DAG ; IP3 Phospholipid-Dependent signaling:
--- through --- activates --- and ---
PLC PIP2 -> DAG
DAG stimulates activity of protein kinase
IP3 stimulates release of Ca2+ and released to cytoplasm
cAMP and PKA ; cGMP ; phospholipid ; JAK/STAT ; MAP kinase cascades signal relay pathways

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hms056