| Term | Definition |
| gastrin | stimulated by small peptides & amino acids in stomach, distention of stomach, vagus; inhibited by H+ in stomach and somatostatin; stimulates H+ secretion and growth of gastric mucosa |
| CCK | stimulated by small peptides, amino acids, fatty acids in duodenum; stimulates secretion of bile from gallbladder, increased pancreatic enzyme and bicarb secretion, growth of exocrine pancreas; inhibits gastric emptying |
| secretin | stimulated by H+ & fatty acids in duodenum; stimulated bicarb secretion from pancreas and gallbladder; decreases gastric H+ production |
| GIP | stimulated by fatty acids, amino acids & glucose in duodenum; increases insulin secretion; decreases gastric H+ secretion |
| somatostatin | stimulated by H+ in lumen of GI tract; inhibited by vagal stimulation; inhibits gastric H+ secretion and release of all GI hormones |
| histamine | secreted by mast cells of gastric mucosa; increases H+ secretion directly and by potentiating gastin and vagal effects |
| VIP | released from neurons in mucosa and smooth muscle of GI tract; produces relaxation of GI smooth muscle; stimulates pancreatic bicarb secretion; inhibits gastric H+ secretion |
| GRP (bombesin) | released from vagus; stimulates gastrin release |
| enkephalins | secreted from nerves in mucosa and smooth muscle of GI; stimulate contraction of smooth muscle; inhibit intestinal secretion of fluid and electrolytes |