| Term | Definition |
| ebullient | excited and enthusiastic or agitated |
| effrontery | brazen or audacity |
| egregious | conspicuous or atrocious |
| elixir | cure all or aid |
| elucidate | to make something clear or annotate |
| elusive | evasive or ambiguous |
| emaciated | very thin and malnourished |
| embellish | to decorate something to make it more attractive or adorn |
| embezzle | to siphon off funds or appropriate |
| embroil | to involve in a quarrel or confound |
| emetic | an agent that causes vomiting |
| emissary | agent or ambassador |
| emollient | softening or soothing agent or application |
| empathize | to relate to another after being through the same experience yourself or ally |
| empyrean | the highest heaven or celestial |
| enamoured | in love or passionate |
| encomium | high praise or commendation |
| endemic | prevalent in or indigenous |
| enervate | to deprive of strength or debilitate |
| enigma | a riddle or bewilderment |
| ennui | bored or apathy |
| entreat | plead or beg |
| enunciate | speak distinctly or affirm |
| ephemeral | short-lived or episodic |
| epicure | one who enjoys and has a discriminating taste for fine food and drink or connoisseur |
| epistemology | study the nature of knowledge |
| epitaph | inscription in the memory of the dead person or commemoration |
| epithet | descriptive word or a phase or description |
| epitome | the best representative of some thing or apotheosis |
| equanimity | calm and balanced or aplomb |
| equivocal | uncertain or ambiguous |
| equivocate | to use evasive language or elude |
| erudite | learned or cultured |
| eschew | avoid or abandon |
| esoteric | understood only by a chosen few or abstruse |
| espouse | adopt or accept |
| exculpate | prove guiltless or absolve |
| exigency | a situation calling for immediate attention or acuteness |
| exiguous | scanty or diminutive |
| exonerate | to free from blame or absolve |
| exorbitant | going behind what is reasonable or exacting |
| expedient | inclined towards methods or means that are advantageous rather than fair or just or advantageous |
| expiate | to make amends for something you have done or absolve |
| expletive | a rude word expressing anger or curse |
| expunge | to cancel or annihilate |
| expurgate | to remove parts of a written |
| extant | still existing or current |
| extenuating | reasons that can make an objectionable action seem less grave |
| extricate | to free or disentangle |