5 Written Questions
5 Matching Questions
- Fluoroquinolones SE
- Erythromycin (E-mycin)
- a The antibiotic class most widely used because of its higher margin of safety and effectiveness.
- b • Similar in structure and function to penicillins
•Have beta-lactam ring; are bacteriocidal
•Widely prescribed anti-infective class
•More than 20 cephalosporins available
•Cross-sensitivity with penicillins (5-10% of population)
•Classified by generations
Generations of cephalosporins
-First (oldest): bacteria producing beta-lactamase are resistant
-Second: more potent, broader spectrum, more resistant to beta-lactamase
-Third: longer duration of action, even broader spectrum, resistant to beta-lactamase
-Fourth: effective against organisms that are resistant to earlier generations
-Third and fourth capable of entering CSF
- c Nausea, diarrhea, vomiting, rash, restlessness, pain and
inflammation at injection site, local burning, stinging and
corneal irritation (ophthalmic)
**Anaphylaxis, tendon rupture, superinfections,
photosensitivity, pseudomembranous colitis
- d Macrolide
- e The small pieces of circular DNA that are transferred through conjugation, which is passing on the resistance gene to other bacteria.
5 Multiple Choice Questions
- Prototype drug: penicillin G (Pentids)
Mechanism of action: to kill bacteria by disrupting their cell walls
Primary use: as drug of choice against streptococci, pneumococci, and staphylococci organisms that do not produce penicillinase
-Also medication of choice for gonorrhea and syphilis
Adverse effects: diarrhea, nausea, vomiting, superinfections, anaphylaxis
- An organism that can cause disease.
- Antibiotics that are used against a wide variety of microorganisms.
- Pharyngitis, pneumonia, skin infections, speticemia, endocarditis
5 True/False Questions
Neomycin sulfate (Mycifradin) → Fluoroquinolone or miscellaneous
Erythromycin (E-mycin) → The antibiotic that would most likely be used for the dental client allergic to penicillin.
Tetracycline → Prototype drug: tetracycline HCL (Achromycin, others)
Mechanism of action: effective against broad range of gram-positive and -negative organisms
Primary use: chlamydiae, rickettsiae, and mycoplasma
Adverse effects: superinfections, nausea, vomiting, epigastric burning, diarrhea, discoloration of teeth, photosensitivity
antibiotic → Refers to natural substances.
Clindamycin (Cleocin) → The antibiotic that would most likely be used for the dental client allergic to penicillin.