5 Written Questions
5 Matching Questions
- Cefepime (Maxipime)
- Ciprofloxacin (Cipro)
- beta-lactam ring
- a Fluoroquinolone or miscellaneous
- b A common word used to describe a pathogen.
- c Cephalosporin
- d The portion of the chemical structure of penicillin that is responsible for its antibacterial activity.
- e Pharyngitis, pneumonia, skin infections, speticemia, endocarditis
5 Multiple Choice Questions
- The process of growing out the pathogen and identifying the most effective antibiotic.
- *FIRST-GENERATION Fluoroquinolones
nalidixic acid (NeoGram) PO; Acute therapy: 1 g qid; PO; Chronic therapy: 500 mg qid
ciprofloxacin (Cipro, Septra) PO; 250-750 mg bid
lomefloxacin (Maxaquin) PO; 400 mg/day
norfloxacin (Noroxin) PO; 400 mg bid
ofloxacin (Floxin) PO; 200-400 mg bid
gatifloxacin (Tequin) PO; 400 mg tid
levofloxacin (Levaquin) PO; 250-500 mg/day
gemifloxacin (Factive) PO; 320 mg/day
moxifloxacin (Avelox) PO; 400 mg/day
trovafloxacin mesylate (Trovan) PO; 100-300 mg/day
- Infections acquired in a hospital or other healthcare setting.
- The value of using an antibiotic that is classified as a broad-spectrum antibiotic.
- Photosensitivity and teeth discoloration are potential adverse effects of this drug.
5 True/False Questions
anti-infectives → Occurs secondarily to anti-infective therapy.
Klebsiella → Cholera
Cephalosporin → Prototype drug: cefotaxime (Claforan)
Mechanism of action: to act with broad-spectrum activity against gram-negative organisms
Primary use: for serious infections of lower respiratory tract, central nervous system, genitourinary system, bones, blood, and joints
Adverse effects: hypersensitivity, anaphylaxis, diarrhea, vomiting, nausea, pain at injection site
bacteriostatic → Bacteria that thrive in an oxygen-rich environment.
Key concept → The cephalosporins are similar in structure and function to the penicillins and are one of the most widely prescribed anti-infective classes. Cross-sensitivity may exist with the penicillins in some clients.