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5 Written questions

5 Matching questions

  1. What is Steven's Johnson Syndrome? What causes it?
  2. Dipenhydramine (Benadryl)
  3. Define absorption
  4. What is c. diff? What causes it? What treats it?
  5. Fluticasone Propionate (Flonase)
  1. a - widespread lesions of skin and mucous membranes
    - fever, malaise, toxemia, can be fatal
    - mostly happens with sulfonamides
  2. b indications: seasonal allergic rhinitis, cold symptoms, allergic reactions, motion sickness, sleep aid (doesn't reduce nasal congestion)
    AE: anticholinergic effects (dry mouth/nose/eyes), urinary retention, constipation, and drowsiness
  3. c cause: clindamycin, amoxicillin, ampicillin, cephalexin
    bacterial infection - contact, hand sanitizer doesn't kill it!
    treatments: metronidiazole (Flagyl) or vanco
  4. d the movement of a drug from its sight of administration into the blood. The rate of absorption determines how soon effects will begin. The amount of absorption helps determine how intense effects will be.
  5. e *inhaled glucocorticoid
    indications: long term asthma, nasal congestion, seasonal and perennial rhinitis
    AE: adrenal suppression and bone loss, oral & pharyngeal candidiasis, disphonia (hoarseness)

5 Multiple choice questions

  1. indications: erectile dysfunction
    AE: hypotension, priapism (long erection), HA, dyspepsia, flushing, nasal congestion, diarrhea, rash, dizziness, mild transient visual disturbances, intensified OSA
    drug interactions: nitrates (causing hypotension), alpha blockers, grapefruit juice can suppress metabolism
  2. indications: duodenal ulcers, gastric ulcers, erosive esophagitis, & GERD. long term treatment of Zollinger Ellison Syndrome
    AE: HA, diarrhea, n/v, gastric ca, hip fx
    MoA: a prodrug, converted to active form inside parietal cells of the stomach, acive form then causes irreversible inhibition of H+, K+-ATPase (proton pump) the enzyme that generates gastric acid
  3. macrovascular damage
    heart disease
    hypertension
    stroke
    hyperglycemia
    altered lipid metabolism
    retinopathy
    nephropathy
    neuropathy
    gastroparesis
    amputations
    erectile dysfunction
  4. indications: bone marrow sparing (chemo), hodgkin's and nonhodgkin's lymphoma, acute lymphocytic leukemia, wilm's tumor, rhabdomyosarcoma, kaposi's syndrome, breast ca, bladder ca
    AE: peripheral neuropathy
    route: IV
  5. indications:pain
    AE: respiratory depression, bradycardia, allergic reactions, constipation
    antidote: narcan, give colace for constipation

5 True/False questions

  1. Define metabolismaka biotransformation
    enzymatically mediated alteration of drug structure

          

  2. How do you mix regular and NPH Insulins?subQ - (abd for most consistency)
    inhalation
    subQ infusion (delivers basal infusion and bolus at mealtime
    IV (regular)

          

  3. Mucinex (guafenesin)indications: relief of non-productive cough from bronchitis, sinusitis, laryngitis
    AE: n/v, gastric irritation, additive or synergistic hypothyroid effect when used concurrently with lithium or any anti-thyroid meds

          

  4. Define a partial agonist-has only moderate intrinsic activity
    -the maximal effect that a partial agonist can produce is lower than that of a full agonist
    - can act as agonists or antagonists

          

  5. Central Acting Anticholinergicsindications: chlamydia, mycoplasma, H. pylori, bacillus anthracis, rocky mt. spotted fever, cholera, lyme disease, acne, and peridontal disease
    AE: GI upset, teeth discoloration, c. diff, candida, hepatotoxic, nephrotoxic, photosensitive, and super infection
    * do not give to pregnant women or children under 8

          

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