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5 Written Questions

5 Matching Questions

  1. Define therapeutic index
  2. Hydrochlorothiazide (HCTZ)
  3. Dronabinol and Marinol
  4. Acetaminophen (Tylenol)
  5. Insulin storage
  1. a * additional anitemetics
    indications: CINV, and increase appetites in clients w/ AIDS
    AE: potential for disocation, disphoria, hypotension, tachycardia, avoid pts w/ mental disorders
  2. b indications: HTN, edema, diabetes insipidus
    AE: hyponatremia, hypochloremia, hypokalemia, dehydration, hyperglycemia, hyperuricemia, increase LDL, increase excretion of mg
    - monitor i/o, weigh pt
    -do not take while pregnant or breast-feeding
    - interacts with digoxin, antihypertensive drugs, lithium, and NSAIDs
  3. c refrigerated until expiration date
    if not refrigerated good for a month
    do not freeze
    keep out of sunlight and extreme heat
  4. d a measure of a drug's safety.
    ratio of a drugs LD (lethal dose) to its ED (effective dose)
    A large (or high) therapeutic index indicated a realitively safe drug, conversely, a small (or low) therapeutic index indicates that a drug is relatively unsafe
  5. e indications: mild pain, fever
    AE: rare, w/ acute toxicity liver damage and death
    liver damage can be minimized w/ mucomyst/acedote
    - don't drink alcohol
    - not an anti-inflammatory

5 Multiple Choice Questions

  1. indications: pulmonary edema (CHF), edema, HTN, renal impairment
    AE: hyponatremia, hypochloremia, dehydration, hypotension, hypokalemia, ototoxicity
  2. indications: decrease drowsiness, fatigue, peripheral vasodilation, CNS vasoconstriction, relaxation of bronchi, neonatal apnea
    AE: convulsions, tinnitus, flashing lights, palpitations, dizziness, diuresis, tachycardia, respiratory stimulation
  3. cause: clindamycin, amoxicillin, ampicillin, cephalexin
    bacterial infection - contact, hand sanitizer doesn't kill it!
    treatments: metronidiazole (Flagyl) or vanco
  4. - toxicity in the kidneys
    - BUN (11-23 mg/dL) and creatinine (0.6-1.2 mg/dL)
    - creatinine clearance in the elderly is the best, collect urine for 24 hrs
  5. indications: anxiety, insomnia, seizure disorders, alcohol withdrawal (diazepam- muscle spasms, alprazolam/conazepam/lorazepam - panic disorder, diazepam/lorazepam/midazolam - preoperative sedation
    - d/c treatment gradually to prevent withdrawal symptoms
    - contraindicate for pregnant or pt w/ sleep apnea
    - caution in pts w/ suicidal tendency or history of alcohol problems
    AE: CNS depression, anterograde amnesia, sleep driving, paradoxical effects (insomnia, euphoria, excitation, heightened anxiety, rage), physical dependence, respiratory depression, abuse, weakness, HA, vertigo, n/v, diarrhea, epigastric distress, blurred vision

5 True/False Questions

  1. Define excretionthe movement of a drug from its sight of administration into the blood. The rate of absorption determines how soon effects will begin. The amount of absorption helps determine how intense effects will be.

          

  2. What is the goal of cancer pain management?indications: ulcers, GERD, Zollinger-Ellison syndrome, aspiration pneumonitis, heartburn, acid indigestion, sour stomach
    AE: rare, but can cause CNS effects, pneumonia, hypotension, dysrhythmias, growth of candida, HA, dizziness, myalgia, nausea, diarrhea, constipation, rash, and pruritis

          

  3. Dipenhydramine (Benadryl)indications: seasonal allergic rhinitis, cold symptoms, allergic reactions, motion sickness, sleep aid (doesn't reduce nasal congestion)
    AE: anticholinergic effects (dry mouth/nose/eyes), urinary retention, constipation, and drowsiness

          

  4. Amphotercin B (Amphotec)indications: inflammation, mild to moderate pain, fever reduction, dysmenorrhea
    AE: mild GI reactions, ulceration, bleeding, increase for MI and stroke, renal impairment, hypersensitivity, reye's syndrome, conjunctivitis, nose bleed, steven's johnson syndrome

          

  5. Sildenafil (Viagra)indications: latent and active TB
    AE: peripheral neuropathy (tingling, numbness, pain in hands & feet, burning) <- give B6 for this
    hepatotoxicity

          

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