| Term | Definition |
|---|
| point mutation | change in a single nucleotide; they can also result from errors in DNA replication or from exposure to mutagenic toxins |
| what are the 4 different types of point mutations? | silent, missence (replacement), nonsense, frame shift |
| silent | change in nucleotides that does not change amino acid specified by codon; *change in genotype but no change in phenotype |
| missence (replacement) | change in nucleotide that changes amino acid specified by codon; * change in primary structure of protein |
| nonsense | change in nucleotide that results in early stop codon; * premature termination- polypeptide is truncated |
| frame-shift | addition or deletion of a nucleotide; *reading frame is shifted- massive missense |
| how does a frame-shift mutation cause a defective protein? | it causes a defective protein by adding a codon that doesn't belong or deletes a codon that belongs in the sequence |
Combine with other sets
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