Set: TCR accessory molecules

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All 9 terms

TermDefinition
CD2(LFA-2)Adhesion and signal transduction(resting T cells/immune & nonimmune cells)
CD58(LFA-3)ligand of CD2Adhesion and signal transduction(resting T cells/immune & nonimmune cells)
CD11aCD18(LFA-1; T cells)Adhesion and signal transduction: augments TH1 response and suppresses TH2 differentiation
CD54(ICAM-1; broad distribution)Adhesion and signal transduction: augments TH1 response and suppresses TH2 differentiation
CD102(ICAM-2; endothelial cells)Adhesion and signal transduction: augments TH1 response and suppresses TH2 differentiation
CD28necessary for T-cell activation; provides 2nd signal for activation
CD152[CTLA-4]ligation by B7 inhibits T-cell activation
CD40L - CD40along with CD28
CD45 - CD22ligand: phophatase, important in dephosphorylation and deactivation of lck
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Set Information

Terms 9
Creator jmcguirk
Created April 13, 2009
Groups None
Subject immunology
Access Anyone
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Description

T cell receptor accessory/costimulatory molecules

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