Milk Release (let-down) after birth in response to suckling.
Afferent neural pathways eminate from sensory nerve endings of alveolae (sacks containing milk) and nipples conduct stimulus to neurohypophysis.
Uterine contractions. OT receptors increase on myometrial cells near labor. Uterine OT initiates birth and pituitary OT contributes to completing birth.
Stimulates PRL secretion during post partum nursing period.
Elicit maternal behaviors
Stimulate human sexual responses
Promote social recognition and social memory
Where is produced? What happens when there are lesions?
Hypothalamus - lesions reduce milk let-down.
What is the target gland for OT?
Mammary gland (modified sebaceous gland)
Receptors for OT on myoepithelial cells that surround alveolus. OT induces contraction of the myoepithelial cells, discharging milk from alveoli into ducts and out of the nipples.
Suckling and uterine contractions stimulate OT (primary)