Respiratory Drugs/gluccocorticoids
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Created by:
KellyODonnell on December 14, 2011
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12 terms
Terms | Definitions |
|---|---|
 Beclomethasone (QVAR) | glucccocorticoid; blocks late reacktion to allergen and airway hyperresponsiveness; decreases edema of airway mucosa; increases # of beta 2 receptors and their responsiveness to beta 2 agonist |
| Deltasone (Prednisone) | gluccocorticoid; orally preferred; short term "burst" (3-10 days) for prompt control of poorly controlled persistent asthma; for long term preventionif s/s in severe persistant asthma |
| Triamcinolone (Azmacort) | gluccocorticoid |
| Cromolyn | antiinflamm; stabalizes the cytoplasmic membrane of mast cells, thereby preventing release of histamine and other mediators; also inhibits eosinophils, macrophages, and other inflammatory cells; used for chronic asthma, bronchospasms induced by exercise (15 min); reduces intensity and frequency of attacks; allergic rhinnits |
| Albuterol (Proventil) | beta 2 agonist; promote bronchodilation, suppresses histamine release in lung, increases ciliary motility; used for asthma attack; if inhaled, fewer s/e |
| Theophylline (Uniphyl) | methylvanthine; check plasma level!!! narrow therapeutic range; leads to gi upset, ulcer, increase hr, hypokalemia, seizure, just like caffeine; oral NOT inhaled!!!; |
| Ipratropium (Atrovent) | anticholinergic antiinflamm.; an atropine derivative; used for COPD, bronchospasm, common cold, quick relief of asthma; slower than albuterol or other beta 2 agonist |
| Loratadine (Claritin) | antihistamine; second generation; blocks action of histamine at histamine receptor sites and inhibits bronchial constriction; avoid with 3rd trimester, nursing mothers, newborns; s/e rare |
| Promethazine (phenergan) | antihistamine; first generation; s/e more common than second gen |
| Dexamethasone (Decadron) | gluccocorticoid; pregnancy C; adrenal corticosteroid; prevents accumulation of inflammatory cells at site of infection, inhibits phago and lysosomal enzyme release; used for adrenal insufficiency, allergic states, collagen disease, hematologic disorders, cerebral edema, Addisonian shock, RA; |
| Prednisone | Adrenal Corticosteroid; pregnancy C; immediate acting synthetic analog of hydrocortisone; used in cancer therapy, myasthenia gravis, |
| Cortisone | synthetic adrenal corticosteroid; Preg D; short acting with prominent glucocorticoid activity; converts to cortisol in body; used for replacement therapy for primary or secondary adrenocortical insufficiency. |
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