Sweet Spring Block 1 Pharmacology (grouped)

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Direct-Acting Muscarinic Agonist

Acetylcholine, Bethanechol, Carbachol, Pilocarpine, Cevimeline

Indirect acting (acetylcholine-esterase inhibitors)

Physostigmine, Neostigmine, Demecarium, Pyridostigmine, Echothiophate, Malathion, Parathion, Sarin, Soman, edrophonium, Donepezil, Galantamine, Rivastigmine.

AChE regeneration

Pralidoxime (2-Pam)

Muscarinic antagonist

Atropine, Dicyclomine, Oxybutynin, Scopolamine, Tolterodine, Tridihexethyl. Clidinium, Cyclopentolate, Glycopyrrolate, Ipratropium, Mepenzolate, Methantheline, Methscopolamine, Propantheline

Ganglion Blockers (anti-nicotinic)

Trimethaphan, Mecamylamine, hexamethonium

Nonspecific adrenoceptor agonist

Epinephrine (all α and βs), Norepinephrine (all but β 2), Dopamine (dose dep)

Beta-adrenoceptor specific agonist

Isoproterenol (β1 and 2), Dobutamine (β1)

Beta 2 receptor specific

Short Acting: Albuterol, Terbutaline, Metaproterenol, Pirbuterol
Long Acting: Salmeterol, Formoterol

Alpha adrenoceptor specific

Phenylephrine, Xylometazoline, Oxymetazoline, Methoxamine, Midodrine

Alpha 2 adrenoceptor specific

Apraclonidine, Brimonidine, Clonidine, Dexmedetomidine

Indirect acting sympathomimetics (increases Norepinephrine at synapse)

Amphetamine, Cocaine, Methamphetamine, Phenmetrazine, Methylphenidate, Pemoline, Modafinil, Phenylpropanolamine, Pseudoephedrine, Ephedrine, Tyramine

Alpha receptor antagonist (non-specific)

Phenoxybenzamine, Phentolamine

Alpha 1 Specific

Alfuzosin, Doxazosin, Prazosin, Terazosin, Tamsulosin

Beta blockers (non-selective, blocks both beta 1 and 2)

Propranolol, Timolol, Carteolol, Carvedilol, Labetalol, Nadolol, Penbutolol, Pindolol, Sotalol, Timolol

Beta 1 selective blockers

Acebutolol, Betaxolol or Bisoprolol, Esmolol, Atenolol, Metoprolol

Partial beta agonist

acebutolol, carteolol, celiprolol, labetalol, penbutolol, pindolol

Beta blockers with local anesthetic properties

Acebutolol, Labetalol, Metoprolol, Pindolol, propranolol

Beta blockers that also blocks alpha receptors

Labetalol and carvedilol

Beta blocker that also blocks potassium channels

Sotalol

Carbonic Anhydrase Inhibitors

Acetazolamide, Dorzolamide, Dichlorphenamide, Methazolamide

Loop Diuretics

Furosemide, Ethacrynic acid, Bumetanide, Torsemide

Thiazides

Bendroflumethiazide, Chlorothiazide, Hydrochlorothiazide, Hydroflumethiazide, Methyclothiazide, Polythiazide, Trichlormethiazide

Sulfonamides similar to Thiazides

Chlorthalidone, Indapamide, Metolazone, Quinethazone

Potassium-sparing Diuretics

Aldosterone antagonists: Eplerenone, Spironolactone
Na+ channel blockers: Amiloride, Triamterene

Osmotic Diuretic

Mannitol

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