| Term | Definition |
| John Smith | Founder of Jamestown and one of the first ever colonists in America. |
| Sir Walter Raleigh | Was a famed English writer, poet, soldier, and explorer. Tried to find El Dorado, wrote about it. |
| Powhatan | Allied with 30 Indian tribes, one of many obstacles faced by Jamestown(1607) |
| Pocahantas | Indian woman saved the life of John Smith and married John Rolfe |
| John Winthrop | led group of Puritans to the New World |
| Cotton Mather | Puritan preacher who had a significant impact on the Salem Witch Trials. |
| Cecilius Calvert | Started the Maryland Colony, was known as Lord Baltimore |
| Nathaniel Bacon | Lead rebellion, in 1676, against Native American raids on the frontier. |
| Roger Williams | Co-founder of Rhode Island, promoted tolerance even with Indians. |
| Anne Hutchinson | went beyond Bible study to proclaim her own theological interpretations of sermons |
| Metacom | Indian leader in the Massachusetts area who led a rebellion against the English. |
| John Culpepper | Congressional representative from North Carolina, Federalist. |
| William Penn | "Absolute Proprietor" of the Province of Pennsylvania, planned Philadephia. |
| Edmund Andros | Governor of the Dominion of New England |
| James Oglethorpe | british philanthropist, founder of colony georgia. |
| John Peter Zenger | Was a newspaper owner in New York City who won an influential case with Alexander Hamilton. |
| Society of Friends | Commonly known as the Quakers, many of which went to Pennsylvania |
| Scots-Irish | Name of those who are of Ulster Scottish descent. Migrated inland to hills for cheap land. |
| John Locke | English philosopher who influenced the declaration with his thinking |
| Benjamin Franklin | founding father and scientist, major figure in enlightenment. |
| George Whitefield | Methodist preacher who came to America to convert its citizens. |
| Jonathan Edwards | Restored spiritual enthusiasm to the Congregational churches in the Connecticut River Valley |
| William Pitt | British politician. Youngest Prime Minister (1783)- 24yrs old. |
| Jamestown | First English settlement, settled in 1607, started by John Smith |
| Roanoke | first english colony in the americans. |
| Mayflower Compact | The first "constitution" for the United States. It was really just a business contract. |
| Plymouth | Founded in 1620, place where the Mayflower landed. |
| Massachusetts Bay Colony | English settlement–east coast of North America (17th century). Centered around Salem and Boston. |
| Masasoit | Leader of the Pokanoket and leader of the Wampanoag Confederacy |
| headright system | attempt to solve labor shortages. |
| Maryland Toleration Acts | The first law in America that allowed for religious freedom. |
| Virginia House of Burgesses | First elected lower house in the Legislative Assembly in the New World |
| Navigation Acts | restricted the use of foreign shipping for trade between England (after 1707 Great Britain) and its colonies |
| Indentured Servants | Poorer people who came to the colonies to work, and would earn their freedom |
| Restoration Colonies | land grants given by king charles. |
| PA Frame of Government | A system of government set up by William Penn that had deep Quaker roots. |
| Dominion of New England | A group of colonies owned by James II, used to enforce Navigation Acts and for defense. |
| the Middle Passage | Passage between Africa and America the Slaves traveled on ships with horrible conditions for around 5 weeks. |
| Salutary Neglect | English government decides not to interfere with colonies |
| Great Awakening | dramatic religious revival in Anglo-American religious history |
| Pontiac's Uprising | a war launched in 1763 by North American First Nations. |
| Seven Years' War | "the French and Indian War" ended France's position as a major colonial power in the Americas. |
| Regulators | unsuccesfully atempted to obtain reforms |
| Albany Plan of Union | A plan for unifying the colonies under one government. It was also proposed by Benjamin Franklin. |